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Peak expiratory flow (PEF) serves as a direct indicator of the functional status of the respiratory system. Higher body fat content, especially abdominal obesity, may relate to a deterioration in long-term res...
Metabolic dysfunction-associated steatotic liver disease (MASLD) has become the most common chronic liver disease, with other fat-liver diseases potentially progressing to cirrhosis and hepatocellular carcinom...
Numerous previous studies have suggested dyslipidemia is possibly linked to endometriosis (EMs). The connection between endometriosis and NHHR remains largely unexplored. Thus, this investigation examined whet...
Although dietary omega fatty acids have been recognized for positive effects on mental health, the specific association between omega fatty acids intake and suicidal ideation remains ambiguous. This study aims...
Although conventional lipids (high density lipoprotein cholesterol (HDLC), low density lipoprotein cholesterol (LDLC), total cholesterol (TC) and triglycerides (TG)) are therapeutic targets to manage and preve...
This study analyzes data from the 2009–2018 National Health and Nutrition Examination Survey (NHANES) to explore the relationship between the Aggregate Index of Systemic Inflammation (AISI), also referred to a...
For over half a century, dietary guidelines have consistently advocated for the substitution of saturated fatty acids (SFA) with monounsaturated (MUFA) and polyunsaturated fatty acids (PUFA) as a cornerstone s...
The widespread presence of per-and polyfluoroalkyl substances (PFAS) has raised global health concerns. This study aims to determine the age-specific relationships of PFAS compounds with metabolic syndrome (Me...
The “lipid paradox” describes the counterintuitive observation that traditionally unfavorable lipid profiles may be associated with improved outcomes in stroke patients. Non-traditional lipid markers such as t...
The relationship between eosinophil number and overweight status (or obesity) remains a subject of debate. While animal studies suggest a negative correlation between the two, most clinical studies indicate a ...
Menopause-related cholesterol metabolic disorders pose a global health concern, but the underlying mechanism is unclear. PRKRA was identified as a potential regulator of cholesterol metabolism in an exome-wide...
Rheumatoid arthritis (RA) is a chronic inflammatory joint disease with increasing mortality worldwide. Traditional obesity indicators inadequately predict the mortality risk in this population. Thus, the resea...
Dysregulated programmed cell death pathways mechanistically contribute to hepatic inflammation and fibrogenesis in non-alcoholic steatohepatitis (NASH). Identification of cell death genes may offer insights in...
This study sought to investigate the independent and synergistic impacts of fasting blood glucose (FBG) and serum uric acid (SUA) levels on non-alcoholic fatty liver disease (NAFLD) in participants with and wi...
Atherosclerosis (AS) is a complex and chronic vascular disease and elevated low-density lipoprotein cholesterol (LDL-C) level is one of its primary causative factors. As a key surface receptor, low-density lip...
Relative fat mass (RFM) is a new metric developed to assess the entire body fat proportion in adults. The objective of this study was to examine the correlation between cognitive performance and RFM in older A...
To investigate the body roundness index (BRI) trajectory categories 12 months post-bariatric surgery and to explore the association between BRI and metabolic abnormalities.
Polyunsaturated fatty acids (PUFAs) have shown notable protective effects in various diseases. This study aims to investigate the associations between PUFAs intake and both chronic constipation (CC) and chroni...
Previous studies have shown an association between obesity and uterine fibroids (UF). Body roundness index (BRI) is an anthropometric measure associated with obesity. However, the association with UF has not b...
Low muscle mass (LMM) is a critical complication in patients with obesity and diabetes, exacerbating metabolic and cardiovascular risks. Novel obesity indices, such as the body roundness index (BRI), conicity ...
This study evaluated the associations of the triglyceride-glucose (TyG) index or its attendant parameters, known as reliable measures of insulin resistance, with asymptomatic intracranial arterial stenosis (aI...
Malignant tumors represent a significant worldwide health challenge, with elevated morbidity and mortality rates necessitating enhanced early identification and individualized treatment. Liposomes, as biomimet...
Previous research has suggested a potential link between urolithiasis and lipid species levels. A Mendelian randomization (MR) study was conducted to investigate whether a causal relationship exists between ge...
Insulin resistance (IR) plays a major role in increasing the risk of stroke. The objective of this research is to systematically evaluate and compare the impact of cumulative exposure over time to four commonl...
Preserved ratio impaired spirometry (PRISm) refers to a form of lung function deterioration, and previous studies have established the association with Chronic Obstructive Pulmonary Disease (COPD). Research ha...
Prediabetes is one of the most common metabolic disorders in the aging process. This study aims to investigate the longitudinal changes in the Cardiometabolic Index (CMI) and their relationship with the natura...
The remnant cholesterol inflammatory index (RCII) is a novel metric that combines remnant cholesterol and high-sensitivity C-reactive protein, reflecting the metabolic and inflammatory risk. This study investi...
Prior studies have indicated a notable link between gut health and metabolic syndrome (MetS). The cardiometabolic index (CMI), an innovative indicator of metabolic health, effectively predicts MetS. Bowel move...
The Cardiometabolic Index (CMI) is a new measure that combines fat distribution and lipid profiles. However, its relationship with rapid decline in renal function and the chronic kidney disease (CKD), especial...
Previous evidence has indicated that insulin resistance may be an early pathological state of preeclampsia (PE). As a novel biomarker, the triglyceride glucose (TyG) index can reflect the level of insulin resi...
The degree to which the triglyceride-glucose (TyG) index might interact with colorectal cancer (CRC) incidence and mortality is undefined. This systematic analysis was conducted through meta-analyses and large...
The prevalence of hyperuricemia (HUA) among Chinese children and adolescents is a significant public health concern. Triglyceride-glucose (TyG) is recognized as a reliable biomarker in predicting insulin resis...
The population of cancer survivors is growing markedly, facing an elevated risk of overall mortality as well as death from cardiovascular diseases (CVDs). Uncovering biomarkers that associated with CVDs among ...
Lipid rafts are specialized microdomains within cellular membranes enriched with cholesterol and sphingolipids that play key roles in cellular organization, signaling, and homeostasis. This review highlights t...
Radiodermatitis (RD) is the primary acute adverse effect experienced by patients receiving radiotherapy (RT) for head and neck cancer (HNC). This study aimed to investigate the correlation between triglyceride...
Ischemic stroke (IS) is one of the leading causes of death and disability worldwide. Early identification of dyslipidemia associated with cerebral atherosclerosis is of great importance for reducing the risk o...
Compare the effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on metabolic dysfunction-associated steatotic liver disease (MASLD), focusing on the mechanisms ...
The uric acid-to-HDL-cholesterol ratio (UHR), a novel marker of metabolism and inflammation, has been investigated in various diseases. However, its potential associations with the incidence of cardiovascular ...
Hypothyroidism may affect triglyceride-rich lipoprotein (TRL) subfractions and low-density lipoprotein (LDL) and their averaged sizes. The present study aimed to determine whether increases in remnant particle...
The original article was published in Lipids in Health and Disease 2025 24:105
Obesity is considered an important risk factor for osteoarthritis (OA), with conicity index (C-index), relative fat mass (RFM) are two novel anthropometric measures of obesity. To investigate the association b...
Visceral adiposity index (VAI) vividly reflects body fat distribution through comprehensively integrating body mass index, sex, waist circumference, triglycerides, and high-density lipoprotein cholesterol. Whi...
Atrial structural remodeling plays a central role in the development and progression of atrial fibrillation (AF) and significantly influences its course. Hyperlipidemia, a potential contributor to AF, affects ...
Apolipoprotein A1 (ApoA1) is a major component of high-density lipoprotein cholesterol and plays a critical role in reverse cholesterol transport. Dynamic changes in ApoA1 levels may be associated with major a...
Obesity is a global health issue which has been widely accepted as an aging related pathogenesis. α-Klotho is a protein involved in aging process, mineral metabolism, insulin sensitivity, and the pathogenesis ...
Remnant cholesterol (RC) causes inflammation and promotes kidney diseases development. However, its role in lupus nephritis (LN) remains unclear. The purpose of this study was to investigate the association be...
The association between remnant cholesterol (RC) with obesity phenotypes remains unclear.
Different dietary choices can influence blood fatty acid profiles, which are crucial for maintaining physiological health and reducing disease risk. In particular, the exclusion of animal foods in vegetarian d...
Dietary antioxidants and obesity are considered significant targets for disease prevention in the elderly. However, a possible cardiometabolic multimorbidity (CMM) correlated to dietary antioxidants and obesit...
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Lipids in Health and Disease