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  1. Lipid Accumulation Product (LAP) is a biomarker associated with excessive lipid accumulation and various metabolic diseases. Despite the well-established link between oral and systemic health, the association ...

    Authors: Li Shuning, Yang Wei, Fan Xuhui, Dong Jianfeng and Liu Jilun
    Citation: Lipids in Health and Disease 2025 24:131
    Content type: Research Published on:

  2. Cardiogenic shock (CS) is a severe cardiac disorder with a high mortality rate. The triglyceride-glucose (TyG) index, a biomarker of insulin resistance, is associated with cardiovascular disease-related mortal...

    Authors: Degang Mo, Peng Zhang, Mengmeng Wang, Jun Guan and Hongyan Dai
    Citation: Lipids in Health and Disease 2025 24:130
    Content type: Research Published on:

  3. Recent studies have suggested an interplay between conicity index (C-index)-related diabetes risk and lipid burden. It is plausible that the atherogenic index of plasma (AIP), fatty liver, and HbA1c mediate th...

    Authors: Yanmei Liu, Rui Shi, Huiying Cao, Jian Zhang, Shuangyue Li, Xilin Kang, Yongjuan Ma, Yudian Wu, Yangfan Guo and Lei Feng
    Citation: Lipids in Health and Disease 2025 24:129
    Content type: Research Published on:

  4. Elevated lipoprotein (a) (Lp(a)) is an independent risk factor for lower extremity artery disease (LEAD) with equivocal effect on amputation and mortality. Results regarding aggressive lipid-lowering therapies...

    Authors: Katrin Gebauer, Nasser M. Malyar, Julian Varghese, Holger Reinecke, Tobias J. Brix and Christiane Engelbertz
    Citation: Lipids in Health and Disease 2025 24:128
    Content type: Research Published on:

  5. Infertility is a multifaceted condition influenced by metabolic and biochemical factors. Uric acid (UA) and high-density lipoprotein cholesterol (HDL-C) may individually affect reproductive health. The UA-to-H...

    Authors: Yanxiang Kong, Miaoling Lin, Yiman Fu, Baoyi Huang, Mengqi Jin and Lin Ma
    Citation: Lipids in Health and Disease 2025 24:127
    Content type: Research Published on:

  6. This study investigates the associations between modified triglyceride-glucose (TyG) indices and the triglyceride-to-high-density lipoprotein (TG/HDL) ratio, which are recognized as simple surrogate indicators...

    Authors: Zihao Zhang, Haihua Guo, Zhen Sun, Dandan Zhang, Yujing Lin, Liangyu Huang, Zexin Guo and Lan Tan
    Citation: Lipids in Health and Disease 2025 24:126
    Content type: Research Published on:

  7. Identifying micro- and macrovascular damage through microalbuminuria and arterial stiffness is essential for preventing renal and cardiovascular complications in patients with type 2 diabetes mellitus (T2D). T...

    Authors: Ling Liu, Yunqiang He, Yan Wang, Juming Tao, Jiachen Wang, Fangzhou Lu, Qi Fu, Tao Yang, Jingyang Gao and Shuai Zheng
    Citation: Lipids in Health and Disease 2025 24:125
    Content type: Research Published on:

  8. Body composition has been associated with various health outcomes, but its specific relationship with arthritis risk remains unclear. The study aimed to examine the associations between lean body mass (LBM) an...

    Authors: Aijun He, Yuyu Cui, Zhening Xu, Zhaoshu Cui, Yanju Li, Jianbo Chang and Xiaoyan Zhou
    Citation: Lipids in Health and Disease 2025 24:124
    Content type: Research Published on:

  9. Evolocumab has shown significant reductions in low-density lipoprotein cholesterol (LDL-C) levels and incident cardiovascular events among acute coronary syndrome (ACS) patients undergoing percutaneous coronar...

    Authors: Yahao Zhang, Kairu Li, Xiangwei Bo, Yanghui Zhang, Tingting Xiao, Huan Liu, Orion I. R. Chiara Villamil, Kui Chen and Jiandong Ding
    Citation: Lipids in Health and Disease 2025 24:123
    Content type: Research Published on:

  10. The relationship between dyslipidemia and mortality varies by age, with an inverse association observed in the oldest age groups. There is limited research examining lipid profiles’ correlation with short-term...

    Authors: Yang Li, Jianli Ge, Shasha Geng, Qingqing Li, Xin Chen, Yingqian Zhu, Xiaotong Guo, Huajie Gu and Yue Liu
    Citation: Lipids in Health and Disease 2025 24:122
    Content type: Research Published on:

  11. Chronic stress in daily life is a well-known trigger for various health issues. Despite advancements in obesity research, the mechanisms governing lipid metabolism in adipose tissue during cachexia remain poor...

    Authors: Yinghua Luo, Qinyu Liu, Yaqian Mao, Junping Wen and Gang Chen
    Citation: Lipids in Health and Disease 2025 24:121
    Content type: Research Published on:

  12. Exposure to brominated flame retardants (BFRs) has been linked to alterations in human metabolism and disease processes. However, the relationship between BFR exposure and blood lipid levels remains unclear. T...

    Authors: Yuxuan Wang, Zhihao Zhang, Nana Shen, Xiaoying Qi, Hao Li, Futong Wu, Zhongze Zhu, Jiarui Liu and Hongfei Xiang
    Citation: Lipids in Health and Disease 2025 24:120
    Content type: Research Published on:

  13. Psoriasis, a prevalent autoimmune skin condition, considerably impairs the quality of life of those who are affected by it. Several studies have demonstrated that obesity significantly contributes to both the ...

    Authors: Xinyi Shao, Jun Yu, Qian Liu, Yidian Fu, Aijun Chen, Genlong Bai and Jingbo Zhang
    Citation: Lipids in Health and Disease 2025 24:119
    Content type: Research Published on:

  14. Visceral adipose tissue (VAT) is strongly associated with metabolic diseases. Both high-intensity interval training (HIT) and moderate-intensity training (MIT) reduce VAT effectively; however, HIT might mediat...

    Authors: Juanjuan Wang, Shuai Tian, Jinchan Du, Sihao Du, Wei Chen and Yang Liu
    Citation: Lipids in Health and Disease 2025 24:118
    Content type: Research Published on:

  15. Several anthropometric indices, such as body mass index and waist circumference, have been used as clinical screening tools for the prediction of nonalcoholic fatty liver disease (NAFLD). To further refine the...

    Authors: Shaghayegh Khanmohammadi, Parisa Fallahtafti, Amirhossein Habibzadeh, Ali Ezzatollahi Tanha, Amir Ali Alamdari, Parsa Fallahtafti and Mohammad Shafi Kuchay
    Citation: Lipids in Health and Disease 2025 24:117
    Content type: Review Published on:

  16. Familial hypercholesterolemia (FH) significantly amplifies the risk of developing atherosclerotic cardiovascular disease (ASCVD). This study investigated the prevalence and clinical characteristics of FH in a ...

    Authors: Tianzhou Shen, Renfei Luo, Hongdong Jiang, Huihui Bao, Long Jiang and Xiaoshu Cheng
    Citation: Lipids in Health and Disease 2025 24:116
    Content type: Research Published on:

  17. Alterations in lipid metabolic pathways constitute a pivotal characteristic of Steroid-Sensitive Nephrotic Syndrome (SSNS). Despite the significance, there has been scant exploration into the influence of poly...

    Authors: Pei-long Li, Hong-min Fu, Kai Liu, Jia-wu Yang, Yuan Liao and Feng Li
    Citation: Lipids in Health and Disease 2025 24:115
    Content type: Research Published on:

  18. Lung cancer remains the leading cause of cancer-related mortality worldwide, necessitating the development of new treatment strategies. Arachidonic acid (ARA), a polyunsaturated fatty acid, shows promise in ca...

    Authors: Lin Wang, Lanlan Wei, Xueling Chen and Jiali Xiong
    Citation: Lipids in Health and Disease 2025 24:114
    Content type: Research Published on:

  19. Metabolic dysfunction-associated steatotic liver disease (MASLD) affects > 25% of the global population, potentially leading to severe hepatic and extrahepatic complications, including metabolic dysfunction-as...

    Authors: Xiaohui Ma, Li Ding, Shuo Li, Yu Fan, Xin Wang, Yitong Han, Hengjie Yuan, Longhao Sun, Qing He and Ming Liu
    Citation: Lipids in Health and Disease 2025 24:113
    Content type: Research Published on:

  20. The established association between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and cardiovascular disease (CVD) risk has been well-documented. Nevertheles...

    Authors: Bingxue Wang, LiYing Li, Ying Tang, Ting Lin, Jing Wu, Guoqi Wang and Xingwu Ran
    Citation: Lipids in Health and Disease 2025 24:112
    Content type: Research Published on:

  21. The atherogenic index of plasma (AIP) can be used to reveal atherosclerosis. This study evaluated the AIP’s efficacy in predicting the prognosis of acute kidney injury (AKI) and severity of acute pancreatitis ...

    Authors: Wen Wu, Yiming Li, Yupei Zhang, Xing Chen, Chunzhen Zhang, Xingguang Qu, Zhaohui Zhang, Rong Zhang and Zhiyong Peng
    Citation: Lipids in Health and Disease 2025 24:111
    Content type: Research Published on:

  22. Dyslipidaemia is a significant risk factor for cardiovascular diseases, which can manifest early in life. Despite its importance, the prevalence of dyslipidaemia in the paediatric population of Pakistan remain...

    Authors: Quratul Ain, Amjad Nawaz, Madeeha Khan, Jaka Sikonja, Hijab Batool, Rabia Zaheer, Mohammad Iqbal Khan, Muhammad Ajmal, Fouzia Sadiq and Urh Groselj
    Citation: Lipids in Health and Disease 2025 24:110
    Content type: Research Published on:

  23. Hypertriglyceridemia is an independent risk factor for cardiovascular diseases. In previous trials, apolipoprotein C-III (APOC3) inhibition through the antisense oligonucleotides volanesorsen, olezarsen, and p...

    Authors: Abdelrahman Mahmoud, Kerollos Abdelsayed, Ahmed Almahdy Mohamed, Qasi Najah, Anas Abdulkader, Karim Ali, Shehroze Tabassum, Mohamed Riad Abouzid, Basel Abdelazeem and James D. Mills
    Citation: Lipids in Health and Disease 2025 24:109
    Content type: Research Published on:

  24. Effective management of hypertriglyceridemia is crucial in the treatment of hypertriglyceridemia-induced acute pancreatitis (HTG-AP). The prognosis of HTG-AP may vary with different serum triglyceride levels, ...

    Authors: Pan Tan, Shasha Lu, Qingxia Chen, Huijian Ma, Wei Kong, Xiawei Huang, Chaohui Yu and Meng Jin
    Citation: Lipids in Health and Disease 2025 24:108
    Content type: Research Published on:

  25. In individuals receiving continuous ambulatory peritoneal dialysis (CAPD), remnant cholesterol (RC) and high-density lipoprotein cholesterol (HDL-C) levels significantly influence clinical outcomes. Current cl...

    Authors: Zebin Wang, Sibing Huang, Na Tian, Qingdong Xu, Xiaojiang Zhan, Fenfen Peng, Xiaoyang Wang, Ning Su, Xiaoran Feng, Xingming Tang, Xianfeng Wu, Qian Zhou, Jianbo Liang, Jiao Li and Yueqiang Wen
    Citation: Lipids in Health and Disease 2025 24:107
    Content type: Research Published on:

  26. Idiopathic nephrotic syndrome (INS) is the most common pediatric glomerular disease, characterized by proteinuria, hypoalbuminemia and edema and caused by an immune dysregulation of T and B cells. Fatty acids ...

    Authors: S. Turolo, A. Edefonti, M. L. Syren, W. Morello, E. A. de Marco, A. Berrettini, C. Agostoni and G. Montini
    Citation: Lipids in Health and Disease 2025 24:106
    Content type: Research Published on:

  27. Hypertension and obesity are common in systemic lupus erythematosus (SLE) patients, with obesity-related changes potentially driving hypertension. However, the specific adiposity measures associated with hyper...

    Authors: Bowen Wang, Liping Zuo, Jinlei Fan, Wei Zhao, Yueming An, Wangshu Cai and Dexin Yu
    Citation: Lipids in Health and Disease 2025 24:105
    Content type: Research Published on:

    The Correction to this article has been published in Lipids in Health and Disease 2025 24:141

  29. Metabolic dysfunction-associated steatotic liver disease (MASLD) is associated with an elevated risk of cardiovascular conditions, such as lower extremity arterial disease (LEAD). The Fibrosis-4 (FIB-4) index,...

    Authors: Chunxia Zhang, Yuchen Ying, Yuanhui Ru, Ziliang Wu, Yumeng Tian, Pingping Shen, Shiyuan Cao, Jing Zhang and Ri Liu
    Citation: Lipids in Health and Disease 2025 24:103
    Content type: Research Published on:

  30. Unhealthy dietary habits have been recognized as key contributors to the increasing incidence of non-communicable diseases. Among the healthy nutrients studied, omega-3 fatty acids, especially eicosapentaenoic...

    Authors: Alessandro Medoro, Francesca Graziano, Gaetano Cardinale, Serena Voccola, Tiziana Zotti, Mariano Intrieri, Giovanni Scapagnini and Sergio Davinelli
    Citation: Lipids in Health and Disease 2025 24:102
    Content type: Research Published on:

  31. & aims: Esophageal cancer (EC) is a tumor type with high invasiveness and poor prognosis, attracting scientists’ attention to its pathogenesis and etiology. Given the limited evidence and conflicting findings reg...

    Authors: Hongming Yin, Yongjin Wang, Yujia Chen, Qayyum Shehzad and Feng Xiao
    Citation: Lipids in Health and Disease 2025 24:101
    Content type: Research Published on:

  32. The high incidence of cardiovascular events in chronic kidney disease (CKD) exhibits an epidemic character, affecting patients in predialysis, hemodialysis, and post-transplant stages, accounting for approxima...

    Authors: Silmara de Melo Carmona, Daniele Pereira Jardim, Maria Aparecida Dalboni, Renata Nakamichi, Mariana Kuniyoshi, Mauro Marrocos, Beata Marie Redublo Quinto and Marcelo Costa Batista
    Citation: Lipids in Health and Disease 2025 24:100
    Content type: Research Published on:

  33. Noncommunicable diseases (NCDs), particularly cardiovascular disease (CVD), are the leading cause of death worldwide, with hypercholesterolemia being a major risk factor for CVD. This study evaluated the hyper...

    Authors: Shirin Djalalinia, Sepehr Khosravi, Moein Yoosefi, Sarvenaz Salahi, Zahra Shokri Varniab, Ali Golestani, Nazila Rezaei, Ameneh Kazemi, Arezou Dilmaghani-Marand, Negar Rezaei, Erfan Ghasemi, Naser Ahmadi, Mohammad-Mahdi Rashidi, Yosef Farzi, Kamyar Rezaee, Maryam Nasserinejad…
    Citation: Lipids in Health and Disease 2025 24:99
    Content type: Research Published on:

  34. Salivary amylase activity (SAA) is recognized as a potential biomarker for metabolic health. Previous studies suggest an association between SAA and insulin sensitivity, but the mechanisms remain unclear. This...

    Authors: Gita Erta, Gita Gersone, Antra Jurka and Peteris Tretjakovs
    Citation: Lipids in Health and Disease 2025 24:98
    Content type: Research Published on:

  35. Insulin resistance and associated metabolic health symptoms remain a primary global health concern. In addition to healthy dietary and nutritional programs, sleep duration is closely related to and has been li...

    Authors: Lei Peng, Yanmei Liu, Yujun Deng, Jianan Jing, Gaohuang Chen, Yang Liu, Maofeng Wu, Jinduan Lin and Weiguo Yin
    Citation: Lipids in Health and Disease 2025 24:97
    Content type: Research Published on:

  36. Surrogate insulin resistance (IR) indices are simpler and more practical alternatives to insulin-based IR indicators for clinical use. This study explored the association between surrogate IR indices, includin...

    Authors: Amirhossein Yadegar, Fatemeh Mohammadi, Kiana Seifouri, Kiavash Mokhtarpour, Sepideh Yadegar, Ehsan Bahrami Hazaveh, Seyed Arsalan Seyedi, Soghra Rabizadeh, Alireza Esteghamati and Manouchehr Nakhjavani
    Citation: Lipids in Health and Disease 2025 24:96
    Content type: Research Published on:

  38. The relationship between the triglyceride glucose (TyG) values and the development of diabetes in non-alcoholic fatty liver disease (NAFLD) patients is not yet well researched. This study aims to examine how t...

    Authors: Xiaomin Liang, Kai Lai, Xiaohong Li, Ying Li, Zemao Xing and Shuiqing Gui
    Citation: Lipids in Health and Disease 2025 24:94
    Content type: Research Published on:

  39. The cardiometabolic index (CMI) serves as a significant marker of diabetes mellitus (DM) and may predict the potential for cardiovascular disease development. Nevertheless, the correlation between CMI and athe...

    Authors: Qiong WEI, Xu Cheng, Min Li, Keying Wu, Meng Chen and Dongmei Zhang
    Citation: Lipids in Health and Disease 2025 24:93
    Content type: Research Published on:

  40. High LDL-cholesterol (LDL-C) is a well-known risk factor for coronary artery disease (CAD). PCSK9, HMGCR, NPC1L1, ACLY, and LDLR gene have been reported as lipid lowering drug genes related to LDL-C lowering. How...

    Authors: Yongho Jee, Jong Won Shin, Mikyung Ryu and Tae-Jin Song
    Citation: Lipids in Health and Disease 2025 24:92
    Content type: Research Published on:

  41. The Atherogenic Index of Plasma (AIP) has been reported as a strong predictor of all-cause mortality in the overall population. However, the lipid profile changes in individuals with end-stage kidney disease (...

    Authors: Yaohua Hu, Liming Yang, Zhanshan Sun, Xiaoxuan Zhang, Xueyan Zhu, Jian Li, Xinyang Li, Mengyuan Yu and Wenpeng Cui
    Citation: Lipids in Health and Disease 2025 24:91
    Content type: Research Published on:

  43. This systematic review explores the hypothesis that various lipid categories and lipid metabolism-related genomic variations link to mental disorders, seeking potential clinically useful markers.

    Authors: Martina Nicole Modesti, Jan Francesco Arena, Antonio Del Casale, Giovanna Gentile, Marina Borro, Giovanna Parmigiani, Maurizio Simmaco, Cecilia Guariglia and Stefano Ferracuti
    Citation: Lipids in Health and Disease 2025 24:89
    Content type: Review Published on:

  44. The MoKaRi study aims to evaluate the impact of two nutritional concepts on cardiometabolic risk factors.

    Authors: Christine Dawczynski, Timo Drobner, Thomas Weidauer, Peter Schlattmann, Michael Kiehntopf, Daniela Weber, Tilman Grune, Winfried März, Marcus E. Kleber and Stefan Lorkowski
    Citation: Lipids in Health and Disease 2025 24:88
    Content type: Research Published on:

  45. The incidence of heart failure (HF), a cardiovascular disease, has been widely reported to be gradually increasing. Although the triglyceride-glucose (TyG) index is associated with the risk of HF, this relatio...

    Authors: Chengyi Wang, Jinxi Wang, Xinqing Li, Ping Zhou, Xuemei Zhao, Anran Xin, Guangzhi Liao, Yan Huang and Yuhui Zhang
    Citation: Lipids in Health and Disease 2025 24:87
    Content type: Research Published on:

  46. Metabolic syndrome, identified by increased visceral fat accumulation, is notably linked to a heightened risk of nephrolithiasis. Despite this, the influence of the perirenal fat thickness relative to renal pa...

    Authors: Dekai Hu, Guoxiang Li, Defeng Ge, Leilei Ke, Hongmin Shu, Yang Chen and Zongyao Hao
    Citation: Lipids in Health and Disease 2025 24:86
    Content type: Research Published on:

  47. Non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR), a new biomarker, reflects blood lipid status. Nevertheless, the association between NHHR and chronic cough remains...

    Authors: Changfen Wang, Xuecheng Liao, Jiulin Chen, Ying Lan and Jun Wen
    Citation: Lipids in Health and Disease 2025 24:85
    Content type: Research Published on:

  48. Frailty is a multifactorial syndrome associated with adverse health outcomes. The metabolic underpinnings of frailty, particularly lipid metabolism, are not fully understood. Unlike isolated lipid fractions or...

    Authors: Shaohua Yan, Ke Chai, Jiefu Yang and Hua Wang
    Citation: Lipids in Health and Disease 2025 24:84
    Content type: Research Published on:

  49. The neutrophil-to-high-density lipoprotein cholesterol ratio (NHR) has emerged as a potential biomarker for chronic disease outcomes. Cognitive impairment is a major contributor to mortality in older adults. H...

    Authors: Anquan Hu, Kun Zhang, Wei Sun, Xian Li, Lianwan Zhou, Xi Li, Feng Chen and Tao Liu
    Citation: Lipids in Health and Disease 2025 24:83
    Content type: Research Published on:

  50. Subclinical hypothyroidism (SCH) contributes to obesity, with the liver acting as a crucial metabolic regulator. Thyroid-stimulating hormone (TSH) affects systemic lipid balance, potentially linking SCH to obe...

    Authors: Shizhan Ma, Yayun Wang, Shuteng Fan, Wanli Jiang, Mingliang Sun, Mengzhe Jing, Wenkai Bi, Meng Zhou and Dongming Wu
    Citation: Lipids in Health and Disease 2025 24:81
    Content type: Research Published on:
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Lipids in Health and Disease

ISSN: 1476-511X