Variables | Total (N = 14,836) | Q1 (N = 2967) | Q2 (N = 2967) | Q3 (N = 2967) | Q4 (N = 2967) | Q5 (N = 2968) | P value |
---|---|---|---|---|---|---|---|
 ≤ 6.86 | 6.86–7.18 | 7.18–7.46 | 7.46–7.76 |  ≥ 7.76 | |||
Demographic | |||||||
 Sex, n (%) |  |  |  |  |  |  |  < 0.001 |
Female | 7801 (52.6) | 2696 (90.9) | 2308 (77.8) | 1493 (50.3) | 782 (26.4) | 522 (17.6) | Â |
Male | 7035 (47.4) | 271 (9.1) | 659 (22.2) | 1474 (49.7) | 2185 (73.6) | 2446 (82.4) | Â |
 Age, Mean ± SD (y) | 60.5 ± 9.8 | 56.5 ± 8.5 | 59.0 ± 8.8 | 60.5 ± 9.2 | 61.5 ± 9.8 | 65.1 ± 10.5 |  < 0.001 |
 Race, n (%) |  |  |  |  |  |  |  < 0.001 |
Non-Han | 970 (6.5) | 222 (7.5) | 199 (6.7) | 181 (6.1) | 167 (5.6) | 201 (6.8) | Â |
Han | 12,388 (83.5) | 2516 (84.8) | 2514 (84.7) | 2510 (84.6) | 2488 (83.9) | 2360 (79.5) | Â |
Unknown | 1478 (10.0) | 229 (7.7) | 254 (8.6) | 276 (9.3) | 312 (10.5) | 407 (13.7) | Â |
 Residence, n (%) |  |  |  |  |  |  | 0.067 |
Urban community | 5583 (37.6) | 1142 (38.5) | 1069 (36.0) | 1093 (36.8) | 1111 (37.4) | 1168 (39.4) | Â |
Rural village | 9253 (62.4) | 1825 (61.5) | 1898 (64.0) | 1874 (63.2) | 1856 (62.6) | 1800 (60.6) | Â |
 Educational Level, n (%) |  |  |  |  |  |  |  < 0.001 |
Illiterate | 6362 (42.9) | 1374 (46.3) | 1461 (49.2) | 1314 (44.3) | 1099 (37) | 1114 (37.5) | Â |
Primary school | 4149 (28.0) | 791 (26.7) | 771 (26.0) | 826 (27.8) | 867 (29.2) | 894 (30.1) | Â |
Junior high school | 2842 (19.2) | 529 (17.8) | 500 (16.9) | 568 (19.1) | 648 (21.8) | 597 (20.1) | Â |
High school or above | 1483 (10.0) | 273 (9.2) | 235 (7.9) | 259 (8.7) | 353 (11.9) | 363 (12.2) | Â |
 Marital status, n (%) |  |  |  |  |  |  |  < 0.001 |
No | 1920 (12.9) | 298 (10.0) | 393 (13.2) | 404 (13.6) | 387 (13.0) | 438 (14.8) | Â |
Yes | 12,916 (87.1) | 2669 (90.0) | 2574 (86.8) | 2563 (86.4) | 2580 (87.0) | 2530 (85.2) | Â |
Health status and function | |||||||
 Height, Mean ± SD (m) | 1.6 ± 0.1 | 1.5 ± 0.1 | 1.6 ± 0.1 | 1.6 ± 0.1 | 1.6 ± 0.1 | 1.6 ± 0.1 |  < 0.001 |
 Weight, Mean ± SD (kg) | 60.1 ± 11.8 | 60.0 ± 13.0 | 58.2 ± 10.2 | 59.8 ± 11.1 | 62.1 ± 11.9 | 60.4 ± 12.4 |  < 0.001 |
 WC, Mean ± SD (cm) | 86.5 ± 10.7 | 81.5 ± 11.5 | 85.0 ± 10.2 | 86.5 ± 10.1 | 88.5 ± 9.5 | 90.7 ± 9.9 |  < 0.001 |
 ABSI**, Mean ± SD | 7.29 ± 0.62 | 6.47 ± 0.62 | 7.02 ± 0.09 | 7.32 ± 0.01 | 7.60 ± 0.08 | 8.05 ± 0.31 |  < 0.001 |
 PEF, Mean ± SD (L/min) | 318.3 ± 125.9 | 294.6 ± 92.3 | 299.7 ± 108.7 | 325.1 ± 129.6 | 349.1 ± 137.7 | 322.8 ± 145.8 |  < 0.001 |
 PEF/PEF prediction, Mean ± SD (%) | 83.7 ± 27.2 | 84.6 ± 23.8 | 84.1 ± 26.0 | 84.0 ± 26.5 | 84.8 ± 27.9 | 81.0 ± 30.9 |  < 0.001 |
 Drinking status, n (%) |  |  |  |  |  |  |  < 0.001 |
No | 7972 (53.7) | 2193 (73.9) | 1994 (67.2) | 1560 (52.6) | 1187 (40.0) | 1038 (35.0) | Â |
Yes | 6864 (46.3) | 774 (26.1) | 973 (32.8) | 1407 (47.4) | 1780 (60.0) | 1930 (65.0) | Â |
 Smoking status, n (%) |  |  |  |  |  |  |  < 0.001 |
Nevera | 8398 (56.6) | 2583 (87.1) | 2264 (76.3) | 1633 (55.0) | 1077 (36.3) | 841 (28.3) | Â |
Currentb | 4175 (28.1) | 233 (7.9) | 479 (16.1) | 927 (31.2) | 1229 (41.4) | 1307 (44.0) | Â |
Pastc | 2263 (15.3) | 151 (5.1) | 224 (7.5) | 407 (13.7) | 661 (22.3) | 820 (27.6) | Â |
 Sleep duration, Mean ± SD (h) | 6.4 ± 1.9 | 6.4 ± 1.9 | 6.3 ± 2.0 | 6.4 ± 2.0 | 6.4 ± 1.9 | 6.5 ± 1.9 | 0.016 |
 Hypertension, n (%) |  |  |  |  |  |  |  < 0.001 |
No | 6136 (41.4) | 1265 (42.6) | 1357 (45.7) | 1256 (42.3) | 1182 (39.8) | 1076 (36.3) | Â |
Yes | 7318 (49.3) | 1321 (44.5) | 1327 (44.7) | 1440 (48.5) | 1542 (52.0) | 1688 (56.9) | Â |
Unknown | 1382 (9.3) | 381 (12.8) | 283 (9.5) | 271 (9.1) | 243 (8.2) | 204 (6.9) | Â |
 Diabetes, n (%) |  |  |  |  |  |  |  < 0.001 |
No | 10,502 (70.8) | 2060 (69.4) | 2129 (71.8) | 2121 (71.5) | 2082 (70.2) | 2110 (71.1) | Â |
Yes | 2418 (16.3) | 420 (14.2) | 471 (15.9) | 446 (15.0) | 525 (17.7) | 556 (18.7) | Â |
Unknown | 1916 (12.9) | 487 (16.4) | 367 (12.4) | 400 (13.5) | 360 (12.1) | 302 (10.2) | Â |
 Heart Diseases, n (%) |  |  |  |  |  |  |  < 0.001 |
No | 10,406 (70.1) | 1978 (66.7) | 2066 (69.6) | 2113 (71.2) | 2113 (71.2) | 2136 (72.0) | Â |
Yes | 2324 (15.7) | 457 (15.4) | 510 (17.2) | 434 (14.6) | 450 (15.2) | 473 (15.9) | Â |
Unknown | 2106 (14.2) | 532 (17.9) | 391 (13.2) | 420 (14.2) | 404 (13.6) | 359 (12.1) | Â |
 Stroke, n (%) |  |  |  |  |  |  |  < 0.001 |
No | 12,350 (83.2) | 2384 (80.4) | 2525 (85.1) | 2473 (83.4) | 2460 (82.9) | 2508 (84.5) | Â |
Yes | 448 (3.0) | 71 (2.4) | 62 (2.1) | 85 (2.9) | 114 (3.8) | 116 (3.9) | Â |
Unknown | 2038 (13.7) | 512 (17.3) | 380 (12.8) | 409 (13.8) | 393 (13.2) | 344 (11.6) | Â |
 Dyslipidemias, n (%) |  |  |  |  |  |  |  < 0.001 |
No | 10,095 (68.0) | 1930 (65.0) | 2046 (69.0) | 2037 (68.7) | 2024 (68.2) | 2058 (69.3) | Â |
Yes | 2346 (15.8) | 460 (15.5) | 478 (16.1) | 460 (15.5) | 467 (15.7) | 481 (16.2) | Â |
Unknown | 2395 (16.1) | 577 (19.4) | 443 (14.9) | 470 (15.8) | 476 (16.0) | 429 (14.5) | Â |
 Kidney Diseases, n (%) |  |  |  |  |  |  |  < 0.001 |
No | 11,458 (77.2) | 2222 (74.9) | 2317 (78.1) | 2310 (77.9) | 2294 (77.3) | 2315 (78.0) | Â |
Yes | 1276 (8.6) | 220 (7.4) | 248 (8.4) | 240 (8.1) | 273 (9.2) | 295 (9.9) | Â |
Unknown | 2102 (14.2) | 525 (17.7) | 402 (13.5) | 417 (14.1) | 400 (13.5) | 358 (12.1) | Â |
Serum biomarkers | |||||||
 Glucose, Mean ± SD (mg/dL) | 103.5 ± 35.2 | 99.8 ± 29.0 | 101.3 ± 30.2 | 102.6 ± 32.8 | 106.0 ± 39.5 | 108.2 ± 42.8 |  < 0.001 |
 Creatinine, Mean ± SD (mg/dL) | 0.8 ± 0.3 | 0.7 ± 0.2 | 0.8 ± 0.3 | 0.8 ± 0.2 | 0.9 ± 0.3 | 0.9 ± 0.4 |  < 0.001 |
 TC, Mean ± SD (mg/dL) | 184.2 ± 36.3 | 187.0 ± 35.5 | 186.5 ± 36.3 | 184.0 ± 36.8 | 183.0 ± 36.1 | 180.3 ± 36.4 |  < 0.001 |
 LDL, Mean ± SD (mg/dL) | 102.4 ± 28.8 | 103.8 ± 28.6 | 103.4 ± 28.7 | 102.4 ± 28.9 | 102.4 ± 29.0 | 99.9 ± 28.8 |  < 0.001 |
 Cystatin C, Mean ± SD (mg/dL) | 0.9 ± 0.2 | 0.8 ± 0.2 | 0.8 ± 0.2 | 0.8 ± 0.2 | 0.9 ± 0.3 | 0.9 ± 0.3 |  < 0.001 |
 TG, Median (IQR) (mg/dL) | 115.9 (83.2, 170.8) | 112.4 (82.3, 166.4) | 116.8 (85.0, 169.0) | 112.4 (81.4, 168.6) | 116.8 (83.2, 176.1) | 117.7 (84.1, 174.3) | 0.021 |