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Table 1 Characteristics stratified by tertiles of conventional lipids

From: Cardiovascular disease risk factors are associated with conventional lipids and apolipoproteins in South African adults of African ancestry

 

Tertile 1

Tertile 2

Tertile 3

p trend

High density lipoprotein cholesterol (mmol/L)

< 1.18

1.18 ≥ to < 1.72

≥ 1.72

 

n

568

566

563

 

Age (years)

49.46 ± 10.43

50.56 ± 10.64

50.34 ± 9.83

0.175

Locality (Urban; %)

276 (48.59)

269 (47.53)

289 (51.33)

0.419

Sex (Men; %)

202 (35.56)a

193 (34.10)b

250 (44.40)a, b

< 0.001

Body mass index (kg/m2)

25.25 (16.87; 39.41)a, c

24.30 (16.68; 38.91)b, c

21.66 (15.70; 34.70)a, b

< 0.001

Physical activity index

7.31 ± 1.94

7.25 ± 1.77

7.27 ± 1.93

0.896

Tobacco use (use; %)

295 (51.94)a

295 (52.12)b

359 (63.77)a, b

< 0.001

Fat intake (kJ)

38.31 (12.82; 106.62)

39.70 (12.71; 115.71)

41.43 (12.37; 112.96)

0.159

γ-Glutamyl transferase (U/L)

45.07 (17.51; 239.87)a

49.96 (18.88; 339.28)b

80.04 (21.79; 469.25)a, b

< 0.001

Glycated haemoglobin (%)

5.71 (4.90; 6.85)a

5.64 (4.80; 6.60)b

5.44 (4.80; 6.10)a, b

< 0.001

C-reactive protein (mg/L)

4.12 (3.64; 4.66)a, c

3.07 (2.71; 3.47)c

2.58 (2.28; 2.91)a

< 0.001

Diuretic medication (use; %)

22 (3.87)

25 (4.42)

11 (1.95)

0.057

Human immunodeficiency virus status (positive; %)

155 (27.29)a, c

67 (11.84)c

59 (10.48)a

< 0.001

Hypertension status (hypertensive; %)

237 (41.73)a

262 (46.29)

302 (53.64)a

< 0.001

Type II diabetes mellitus status (diabetic; %)

47 (8.27)a

35 (6.19)b

10 (1.78)a, b

< 0.001

Adiposity status (Overweight and obese; %)

272 (48.06)a

244 (43.26)b

134 (23.80)a, b

< 0.001

Low density lipoprotein cholesterol (mmol/L)

< 2.31

≥ 2.31 to < 3.30

≥ 3.30

 

n

566

565

566

 

Age (years)

48.73 ± 9.27a

49.87 ± 10.42b

51.76 ± 10.97a, b

< 0.001

Locality (Urban; %)

276 (48.76)

276 (48.85)

282 (49.82)

0.925

Sex (Men; %)

282 (49.82)a, c

201 (35.58)b, c

162 (28.62)a, b

< 0.001

Body mass index (kg/m2)

21.87 (15.76; 36.22)a, c

23.60 (16.24; 38.95)b, c

25.76 (17.81; 39.89)a, b

< 0.001

Physical activity index

7.28 ± 1.86

7.32 ± 2.01

7.24 ± 1.76

0.765

Tobacco use (use; %)

358 (63.25)a, c

306 (54.16)c

285 (50.35)a

< 0.001

Fat intake (kJ)

38.35 (11.41; 114.63)

40.11 (15.28; 105.99)

40.94 (13.01; 113.67)

0.280

γ-Glutamyl transferase (U/L)

60.56 (18.32; 407.55)

54.59 (19.00; 379.59)

54.40 (19.32; 303.85)

0.085

Glycated haemoglobin (%)

5.46 (4.70; 6.30)a, c

5.62 (4.90; 6.67)c

5.70 (4.90; 6.76)a

< 0.001

C-reactive protein (mg/L)

3.08 (2.70; 3.51)

2.84 (2.51; 3.22)b

3.73 (3.33; 4.18) b

0.005

Diuretic medication (use; %)

12 (2.12)a

18 (3.19)

28 (4.95)a

0.030

Human immunodeficiency virus status (positive; %)

114 (20.14)a

110 (19.47)b

57 (10.07)a, b

< 0.001

Hypertension status (hypertensive; %)

251 (44.35)

264 (46.73)

286 (50.53)

0.090

Type II diabetes mellitus status (diabetic; %)

19 (3.36)a

34 (6.03)

39 (6.89)a

0.024

Adiposity status (Overweight and obese; %)

146 (25.80)a, c

212 (37.59)b, c

292 (51.77)a, b

< 0.001

Total cholesterol (mmol/L)

< 4.32

≥4.32 to < 5.48

≥ 5.48

 

n

566

564

567

 

Age (years)

48.10 ± 9.57a, c

50.43 ± 10.34c

51.83 ± 10.67a

< 0.001

Locality (Urban; %)

268 (47.35)

274 (48.58)

292 (51.50)

0.357

Sex (Men; %)

259 (45.76)a, c

208 (36.88)c

178 (31.39)a

< 0.001

Body mass index (kg/m2)

22.54 (16.01; 37.40)a, c

23.62 (16.23; 37.46)b, c

24.97 (17.24; 39.27)a, b

< 0.001

Physical activity index

7.32 ± 1.92

7.29 ± 1.92

7.22 ± 1.81

0.610

Tobacco use (use; %)

344 (60.78)a

313 (55.50)

292 (51.50)a

0.006

Fat intake (kJ)

38.33 (11.87; 113.10)

39.48 (12.76; 109.31)

41.61 (13.17; 112.47)

0.123

γ-Glutamyl transferase (U/L)

49.19 (17.46; 325.43) a, c

57.02 (19.24; 373.89)c

64.11 (21.02; 379.11)a

< 0.001

Glycated haemoglobin (%)

5.49 (4.80; 6.30)a, c

5.61 (4.80; 6.50)c

5.68 (4.90; 6.86)a

< 0.001

C-reactive protein (mg/L)

3.16 (2.76; 3.61)

2.96 (2.62; 3.34)

3.49 (3.12; 3.92)

0.142

Diuretic medication (use; %)

9 (1.59)a, c

24 (4.26)c

25 (4.41)a

0.013

Human immunodeficiency virus status (positive; %)

145 (25.62)a, c

86 (15.25)b, c

50 (8.82)a, b

< 0.001

Hypertension status (hypertensive; %)

226 (39.93)a, c

270 (47.87)c

305 (53.79)a

< 0.001

Type II diabetes mellitus status (diabetic; %)

21 (3.71)

33 (5.86)

38 (6.70)

0.072

Adiposity status (Overweight and obese; %)

173 (30.62)a, c

212 (38.26)b, c

262 (46.29)a, b

< 0.001

Triglyceride (mmol/L)

< 0.89

≥ 0.89 to < 1.38

≥ 1.38

 

n

571

574

552

 

Age (years)

48.15 ± 9.89a, c

50.21 ± 10.32b, c

52.06 ± 10.38a, b

< 0.001

Locality (Urban; %)

269 (47.11)a

253 (44.08)b

312 (56.52)a, b

< 0.001

Sex (Men; %)

264 (46.23)a, c

210 (36.59)c

171 (30.98)a

< 0.001

Body mass index (kg/m2)

22.05 (16.17; 34.54)a, c

23.25 (15.82; 37.34)b, c

26.01 (17.83; 41.10)a, b

< 0.001

Physical activity index

7.38 ± 1.79

7.25 ± 1.88

7.20 ± 1.97

0.249

Tobacco use (use; %)

344 (60.24)a

322 (56.10)

283 (51.27)a

0.012

Fat intake (kJ)

38.73 (12.69; 109.64)

38.76 (11.99; 108.52)

42.05 (13.22; 115.28)

0.074

γ-Glutamyl transferase (U/L)

51.30 (17.42; 380.31)a

53.72 (19.00; 339.03)b

65.63 (20.72; 380.04)a, b

< 0.001

Glycated haemoglobin (%)

5.46 (4.80; 6.10)a, c

5.54 (4.77; 6.40)b, c

5.80 (4.90; 7.70)a, b

< 0.001

C-reactive protein (mg/L)

2.56 (2.25; 2.90)a, c

3.32 (2.93; 3.76)c

3.88 (3.45; 4.36)a

< 0.001

Diuretic medication (use; %)

8 (1.40)a

18 (3.14)

32 (5.80)a

< 0.001

Human immunodeficiency virus status (positive; %)

93 (16.29)

107 (18.64)

81 (14.67)

0.187

Hypertension status (hypertensive; %)

235 (41.16)a

251 (43.73)b

315 (57.07)a, b

< 0.001

Type II diabetes mellitus status (diabetic; %)

11 (1.93)a

23 (4.01)b

58 (10.50)a, b

< 0.001

Adiposity status (Overweight and obese; %)

154 (27.07)a, c

206 (35.89)b, c

290 (52.73)a, b

< 0.001

  1. Unadjusted results are presented as arithmetic mean ± standard deviation, geometric mean with 5th and 95th percentile intervals, or frequency and percentage
  2. Superscript letters indicate significance for between tertile differences
  3. Abbreviations: n, number of participants; CVD, cardiovascular disease