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Table 4 Risk of metabolic abnormalities at T12 by BRI trajectory

From: Body roundness index trajectories in Chinese bariatric surgery patients: a retrospective longitudinal study

Metabolic Biomarkers

BRI trajectory

All patients (n = 669)

 

Subgroup analysis of participants with abnormalities at T0 #

Low-gradual decline (n = 539)

High-rapid decline (n = 76)

High-gradual decline (n = 54)

 

High-rapid decline

High-gradual decline

OR(95%CI)

OR(95%CI)

P

OR(95%CI)

P

 

OR(95%CI)

P

OR(95%CI)

P

Model 0

          

TG

1.00 (Ref)

1.93 (0.99 ~ 3.75)

0.051

3.28 (1.67 ~ 6.42)

0.001*

 

1.11 (0.43 ~ 2.85)

0.828

4.24 (1.77 ~ 10.18)

0.001*

HDL-C

1.00 (Ref)

2.84 (1.73 ~ 4.67)

< 0.001*

4.30 (2.31 ~ 8.00)

< 0.001*

 

2.61 (1.42 ~ 4.82)

0.002*

4.11 (1.90 ~ 8.90)

< 0.001*

LDL-C

1.00 (Ref)

1.03 (0.54 ~ 1.95)

0.929

2.10 (1.12 ~ 3.93)

0.020*

 

1.53 (0.69 ~ 3.38)

0.297

3.39 (1.34 ~ 8.61)

0.010*

GLU

1.00 (Ref)

1.63 (0.99 ~ 2.67)

0.052

1.09 (0.60 ~ 1.99)

0.783

 

2.24 (0.98 ~ 5.10)

0.055

1.05 (0.43 ~ 2.57)

0.909

UA

1.00 (Ref)

1.54 (0.95 ~ 2.51)

0.081

2.33 (1.33 ~ 4.10)

0.003*

 

1.33 (0.77 ~ 2.28)

0.311

1.88 (0.94 ~ 3.77)

0.073

Model 1

          

TG

1.00 (Ref)

1.66 (0.84 ~ 3.29)

0.145

3.40 (1.68 ~ 6.85)

0.001*

 

1.05 (0.39 ~ 2.81)

0.909

4.47 (1.76 ~ 11.32)

0.002*

HDL-C

1.00 (Ref)

2.90 (1.74 ~ 4.85)

< 0.001*

4.40 (2.33 ~ 8.33)

< 0.001*

 

2.51 (1.34 ~ 4.70)

0.004*

4.40 (1.98 ~ 9.74)

< 0.001*

LDL-C

1.00 (Ref)

1.04 (0.54 ~ 2.02)

0.885

2.03 (1.06 ~ 3.87)

0.031*

 

1.62 (0.7 ~ 3.76)

0.258

3.90 (1.46 ~ 10.40)

0.006*

GLU

1.00 (Ref)

1.38 (0.82 ~ 2.33)

0.223

0.89 (0.47 ~ 1.67)

0.892

 

2.34 (0.88 ~ 6.19)

0.086

0.85 (0.31 ~ 2.30)

0.753

UA

1.00 (Ref)

1.38 (0.83 ~ 2.28)

0.209

2.61 (1.45 ~ 4.67)

0.001*

 

1.19 (0.67 ~ 2.08)

0.543

2.05 (0.99 ~ 4.18)

0.051

Model 2

          

TG

1.00 (Ref)

1.69 (0.86 ~ 3.33)

0.128

2.63 (1.29 ~ 5.34)

0.008*

 

1.01 (0.39 ~ 2.66)

0.969

3.54 (1.38 ~ 9.10)

0.009*

HDL-C

1.00 (Ref)

2.67 (1.61 ~ 4.43)

< 0.001*

3.79 (2.01 ~ 7.16)

< 0.001*

 

2.50 (1.35 ~ 4.63)

0.004*

3.65 (1.66 ~ 8.05)

0.001*

LDL-C

1.00 (Ref)

0.87 (0.45 ~ 1.68)

0.678

1.57 (0.81 ~ 3.06)

0.179

 

1.28 (0.55 ~ 2.94)

0.559

2.57 (0.96 ~ 6.85)

0.058

GLU

1.00 (Ref)

1.62 (0.98 ~ 2.67)

0.058

1.07 (0.57 ~ 1.99)

0.820

 

2.26 (0.98 ~ 5.19)

0.054

1.13 (0.45 ~ 2.83)

0.795

UA

1.00 (Ref)

1.50 (0.91 ~ 2.47)

0.106

2.17 (1.21 ~ 3.88)

0.009*

 

1.27 (0.73 ~ 2.21)

0.396

1.67 (0.82 ~ 3.44)

0.157

Model 3

          

TG

1.00 (Ref)

1.86 (0.92 ~ 3.76)

0.083

3.23 (1.64 ~ 6.38)

0.001*

 

1.10 (0.41 ~ 2.93)

0.838

4.00 (1.63 ~ 9.78)

0.002*

HDL-C

1.00 (Ref)

2.56 (1.52 ~ 4.32)

< 0.001*

4.18 (2.23 ~ 7.81)

< 0.001*

 

2.39 (1.24 ~ 4.60)

0.009*

4.09 (1.88 ~ 8.91)

< 0.001*

LDL-C

1.00 (Ref)

1.11 (0.56 ~ 2.18)

0.746

2.18 (1.15 ~ 4.12)

0.016*

 

1.53 (0.64 ~ 3.66)

0.330

3.47 (1.34 ~ 8.98)

0.010*

GLU

1.00 (Ref)

1.58 (0.92 ~ 2.73)

0.098

1.11 (0.60 ~ 2.04)

0.724

 

2.36 (0.98 ~ 5.63)

0.053

1.02 (0.41 ~ 2.54)

0.950

UA

1.00 (Ref)

1.64 (0.98 ~ 2.75)

0.057

2.39 (1.35 ~ 4.22)

0.003*

 

1.37 (0.77 ~ 2.46)

0.279

1.93 (0.96 ~ 3.89)

0.065

Model 4

          

TG

1.00 (Ref)

1.35 (0.64 ~ 2.83)

0.427

2.66 (1.26 ~ 5.63)

0.010*

 

0.91 (0.32 ~ 2.53)

0.857

3.33 (1.21 ~ 9.19)

0.020*

HDL-C

1.00 (Ref)

2.35 (1.36 ~ 4.06)

0.002*

3.63 (1.88 ~ 7.01)

< 0.001*

 

2.11 (1.07 ~ 4.16)

0.030*

3.83 (1.68 ~ 8.70)

0.001*

LDL-C

1.00 (Ref)

0.83 (0.40 ~ 1.71)

0.628

1.52 (0.76 ~ 3.06)

0.233

 

1.16 (0.44 ~ 3.05)

0.755

2.99 (1.06 ~ 8.41)

0.037*

GLU

1.00 (Ref)

1.47 (0.83 ~ 2.58)

0.181

0.92 (0.47 ~ 1.78)

0.811

 

2.27 (0.79 ~ 6.52)

0.127

0.88 (0.30 ~ 2.56)

0.814

UA

1.00 (Ref)

1.43 (0.83 ~ 2.46)

0.191

2.52 (1.37 ~ 4.62)

0.003*

 

1.14 (0.61 ~ 2.11)

0.678

1.89 (0.89 ~ 4.00)

0.096

  1. Notes: # indicates the sample size of participants with abnormalities at T0, the specific sample size: TG (n = 324), HDL-C (n = 465), LDL-C (n = 270), GLU (n = 255), UA (n = 439). *indicates P < 0.05. Model 0: crude model without any adjustments; Model 1: adjusted for demographic information (gender, age, marital status, employment status and educational attainment); Model 2: adjusted for baseline lifestyle factors (dietary behavior, physical activity and sleep quality); Model 3: adjusted for surgical procedures; Model 4: adjusted for Model 1 ~ 3. Abbreviations: T0, baseline; OR, odds ratio; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; GLU, glucose; UA, uric acid;