| Total (n = 7,565) | Q1 (n = 1,770) | Q2 (n = 1,885) | Q3 (n = 1,933) | Q4 (n = 1,977) | P |
---|---|---|---|---|---|---|
Age, years | 59.95 (10.44) | 58.04 (8.97) | 60.16 (9.84) | 60.97 (9.38) | 60.63 (10.97) |  < 0.001 |
Female | 3848 (53.28) | 801 (48.19) | 871 (48.36) | 993 (52.88) | 1183 (63.64) |  < 0.001 |
Race |  |  |  |  |  |  < 0.001 |
Mexican American | 1347 (4.55) | 204 (2.85) | 338 (4.61) | 383 (5.07) | 422 (5.69) | Â |
Other Hispanic | 485 (4.16) | 111 (3.29) | 113 (3.59) | 140 (5.26) | 121 (4.48) | Â |
Non-Hispanic White | 4146 (77.84) | 1023 (77.80) | 1068 (80.32) | 1027 (76.86) | 1028 (76.38) | Â |
Non-Hispanic Black | 1324 (9.04) | 329 (8.68) | 308 (8.41) | 328 (8.89) | 359 (10.17) | Â |
Other Race | 263 (4.41) | 103 (7.38) | 58 (3.07) | 55 (3.92) | 47 (3.28) | Â |
Education |  |  |  |  |  |  < 0.001 |
Less than high school | 2548 (21.56) | 438 (14.68) | 619 (21.36) | 725 (22.79) | 766 (27.43) | Â |
High school graduate or higher | 5000 (78.44) | 1331 (85.32) | 1264 (78.64) | 1203 (77.21) | 1202 (72.57) | Â |
Marital status |  |  |  |  |  |  < 0.001 |
Not married or living with a partner | 2761 (30.61) | 574 (25.91) | 657 (29.66) | 713 (30.84) | 817 (36.05) | Â |
Married or living with a partner | 4705 (69.39) | 1179 (74.09) | 1202 (70.34) | 1199 (69.16) | 1125 (63.95) | Â |
Drinking | 4754 (69.74) | 1196 (75.02) | 1221 (71.38) | 1215 (67.79) | 1122 (64.76) |  < 0.001 |
Smoking | 3956 (53.60) | 848 (49.83) | 970 (52.35) | 1040 (52.44) | 1098 (59.77) |  < 0.001 |
Dyslipidemia | 6258 (83.28) | 1291 (72.81) | 1528 (82.72) | 1690 (87.57) | 1749 (89.96) |  < 0.001 |
Hypertension | 4438 (52.12) | 860 (39.38) | 1095 (51.20) | 1180 (55.50) | 1303 (62.37) |  < 0.001 |
Chronic Kidney Disease | 2028 (20.44) | 361 (14.67) | 481 (18.33) | 551 (21.66) | 635 (27.09) |  < 0.001 |
Diabetes mellitus | 1886 (18.53) | 328 (12.69) | 410 (15.63) | 520 (20.41) | 628 (25.38) |  < 0.001 |
Cancer | 1075 (13.91) | 242 (12.57) | 255 (12.92) | 261 (13.66) | 317 (16.48) | 0.013 |
Coronary Heart Disease | 528 (6.10) | 105 (4.93) | 135 (6.53) | 148 (6.57) | 140 (6.36) | 0.346 |
Stroke | 445 (4.32) | 82 (2.85) | 97 (3.58) | 112 (4.56) | 154 (6.28) |  < 0.001 |
SBP, mmHg | 128.00 (116.00, 142.00) | 122.00 (112.00, 136.00) | 126.00 (116.00, 140.00) | 130.00 (118.00, 144.00) | 132.00 (118.00, 144.00) |  < 0.001 |
BMI, kg/m^2 | 27.65 (24.27, 31.70) | 24.70 (22.15, 27.67) | 27.19 (24.40, 30.49) | 28.78 (25.52, 32.57) | 30.82 (26.70, 36.21) |  < 0.001 |
TC, mg/dL | 204.00 (180.00, 231.00) | 200.00 (177.00, 224.00) | 203.00 (178.00, 230.00) | 206.00 (183.00, 234.00) | 208.00 (184.00, 237.00) |  < 0.001 |
HDL-C, mg/dL | 52.00 (43.00, 64.00) | 59.00 (49.00, 71.00) | 52.00 (44.00, 65.00) | 49.00 (42.00, 60.00) | 47.00 (40.00, 58.00) |  < 0.001 |
LDL-C, mg/dL | 122.00 (100.00, 146.00) | 118.00 (98.00, 141.00) | 123.00 (99.00, 145.00) | 123.00 (103.00, 151.00) | 124.00 (100.00, 148.00) |  < 0.001 |
TG, mg/dL | 123.00 (89.00, 174.00) | 88.00 (67.00, 113.00) | 115.00 (86.00, 159.00) | 140.00 (106.00, 187.00) | 164.00 (125.00, 227.00) |  < 0.001 |
WBC, 10^3/μL | 6.71 (2.32) | 5.97 (1.40) | 6.45 (2.03) | 6.79 (1.76) | 7.63 (2.37) |  < 0.001 |
Platelets, 10^3/μL | 258.57 (82.34) | 242.68 (61.99) | 249.60 (58.47) | 261.87 (51.59) | 280.02 (96.63) |  < 0.001 |
eGFR, mL/min/1.73 m2 | 92.42 (76.55, 104.90) | 94.21 (80.65, 105.76) | 92.16 (77.22, 106.68) | 92.35 (75.75, 104.46) | 90.50 (73.14, 104.64) |  < 0.001 |
Uric acid, mg/dL | 5.50 (4.60, 6.50) | 5.00 (4.20, 5.90) | 5.50 (4.50, 6.40) | 5.70 (4.70, 6.60) | 5.80 (4.90, 6.80) |  < 0.001 |
HbA1c, % | 5.50 (5.30, 5.80) | 5.40 (5.20, 5.70) | 5.50 (5.20, 5.70) | 5.50 (5.30, 5.90) | 5.60 (5.30, 6.00) |  < 0.001 |
FPG, mg/dL | 100.50 (93.50, 110.90) | 97.20 (92.00, 105.10) | 100.00 (93.90, 109.60) | 101.10 (94.40, 111.60) | 103.80 (95.40, 115.90) |  < 0.001 |
CRP, mg/dL | 0.23 (0.10, 0.51) | 0.06 (0.04, 0.09) | 0.16 (0.12, 0.22) | 0.32 (0.24, 0.44) | 0.86 (0.58, 1.37) |  < 0.001 |
RC, mg/dL | 25.00 (18.00, 35.00) | 18.00 (13.00, 23.00) | 23.00 (17.00, 32.00) | 28.00 (21.00, 38.00) | 33.00 (25.00, 45.00) |  < 0.001 |
RCII | 5.76 (2.21, 14.49) | 1.08 (0.65, 1.65) | 3.64 (2.88, 4.60) | 8.99 (7.14, 11.31) | 27.14 (19.00, 41.60) |  < 0.001 |
lnRCII | 1.71 (1.74) | − 0.08 (0.56) | 1.29 (0.29) | 2.19 (0.29) | 3.42 (0.59) |  < 0.001 |
All-cause deaths | 2698 (30.62) | 502 (21.21) | 641 (28.44) | 722 (34.12) | 833 (38.67) |  < 0.001 |
CVD deaths | 860 (9.39) | 165 (6.26) | 219 (9.45) | 216 (10.30) | 260 (11.54) |  < 0.001 |
Cancer deaths | 613 (7.19) | 108 (5.38) | 150 (6.96) | 166 (7.61) | 189 (8.80) | 0.017 |