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Table 1 Weighted characteristics of participants in study

From: Development and validation of machine learning models for predicting low muscle mass in patients with obesity and diabetes

Characteristic

Normal muscle mass (n = 1713)

Low muscle mass (n = 463)

P-value

Age (years)

53.00 (48.00, 56.00)

52.58 (44.00, 55.00)

0.420

WC (cm)

113.00 (102.98, 124.30)

117.80 (108.50, 135.50)

0.067

BMI (kg/m2)

33.70 (29.20, 37.30)

37.80 (32.30, 43.70)

< 0.001***

White blood cell count (109/L)

7.90 (6.70, 9.10)

8.30 (7.40, 9.40)

0.045*

Lymphocyte count (109/L)

2.20 (1.70, 2.70)

2.20 (2.00, 2.70)

0.146

Monocyte count (109/L)

0.60 (0.50, 0.70)

0.60 (0.50, 0.70)

0.551

Neutrophil count (109/L)

4.60 (3.70, 5.90)

5.05 (4.30, 6.00)

0.090

Hemoglobin (g/L)

14.40 (13.30, 15.40)

14.30 (13.20, 15.00)

0.473

Red cell distribution width (%)

13.50 (12.90, 14.10)

13.60 (13.20, 14.10)

0.411

Fasting glucose (mmol/L)

8.99 (7.11, 12.56)

7.12 (6.27, 9.63)

0.097

Albumin (g/L)

42.00 (40.00, 44.00)

41.00 (40.00, 44.00)

0.898

Globulin (g/L)

28.00 (26.00, 31.00)

29.00 (27.00, 33.00)

0.039*

Creatinine (umol/L)

74.26 (63.65, 90.17)

70.72 (61.88, 76.02)

0.005**

Uric acid (umol/L)

321.20 (255.80, 392.60)

327.10 (255.80, 379.58)

0.851

HbA1c (%)

7.20 (6.30, 8.90)

6.60 (6.10, 8.60)

0.017*

ALT (U/L)

25.00 (19.00, 37.00)

29.00 (23.00, 43.00)

0.070

AST (U/L)

25.00 (19.00, 30.00)

24.00 (20.00, 34.00)

0.749

ALP (U/L)

70.00 (57.00, 89.00)

72.00 (57.00, 91.00)

0.583

Low-density lipoprotein (mmol/L)

2.48 (1.94, 3.38)

2.87 (2.28, 4.03)

0.172

High-density lipoprotein (mmol/L)

1.14 (0.96, 1.29)

1.11 (0.98, 1.34)

0.628

Total cholesterol (mmol/L)

4.68 (3.88, 5.59)

4.60 (4.14, 5.87)

0.306

Triglyceride (mmol/L)

2.16 (1.21, 3.16)

1.67 (1.46, 2.36)

0.279

Systolic pressure (mmHg)

123.00 (113.00, 132.00)

123.00 (116.00, 138.00)

0.259

Diastolic pressure (mmHg)

74.00 (68.00, 80.00)

71.00 (67.00, 77.00)

0.198

SMI

0.80 (0.61, 0.92)

0.51 (0.49, 0.74)

< 0.001***

Total body fat percent (%)

35.50 (30.50, 41.50)

41.80 (35.90, 46.20)

< 0.001***

BRI

6.73 (5.43, 8.85)

9.11 (7.60, 10.99)

< 0.001***

RFM

38.24 (32.13, 47.48)

45.01 (37.13, 49.41)

0.001**

C-index

1.08 (0.94, 1.25)

1.01 (0.81, 1.20)

0.086

Gender, n (%)

  

0.395

Female

940 (54.9)

277 (59.8)

 

Male

773 (45.1)

186 (40.2)

 

Race, n (%)

  

0.005**

Mexican American

227 (13.3)

142 (30.7)

 

Other Hispanic

168 (9.8)

80 (17.3)

 

Non-Hispanic White

574 (33.5)

161 (34.8)

 

Non-Hispanic Black

540 (31.5)

47 (10.2)

 

Other race

204 (11.9)

33 (7.1)

 

Drinking status, n (%)

  

0.046*

Drinker

629 (36.7)

123 (26.6)

 

Non-drinker

1084 (63.3)

340 (73.4)

 

Smoking status, n (%)

  

0.860

Smoker

917 (53.5)

252 (54.4)

 

Non-smoker

796 (46.5)

211 (45.6)

 

Use of insulin, n (%)

  

0.275

Yes

1185 (69.2)

348 (75.2)

 

No

528 (30.8)

115 (24.8)

 

Use of metformin, n (%)

  

0.882

Yes

1418 (87.4)

386 (87.1)

 

No

204 (12.6)

57 (12.9)

 
  1. Data are presented as median (IQR), or n (%). Abbreviations: WC, Waist circumference; BMI, Body mass index; HbA1c, glycated hemoglobin; ALT, Alanine transaminase; AST, Alanine aminotransferase; ALP, Alkaline phosphatase; SMI, skeletal muscle mass index; BRI, body roundness index; RFM, relative fat mass; C-index, conicity index; IQR, interquartile range. * P < 0.05, ** P < 0.01, *** P < 0.001
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Lipids in Health and Disease

ISSN: 1476-511X