The association between Glycated Hemoglobin to High Density Lipoprotein Cholesterol Ratio and risk of cardiovascular diseases caused death among adult cancer survivors: evidence from NHANES 1999–2018

Table 2 The age-stratified Cox proportional hazards model, adjusted for different covariables, investigated the association between GH/HDL-C levels and the risk of CVDs mortality among cancer survivors

Variables		Model 1		Model 2		Model 3
Variables		HR (95%CI)	P	HR (95%CI)	P	HR (95%CI)	P
< 60years	GH/HDL-C	1.31 (1.19–1.45)	< 0.001	1.11(0.91–1.37)	0.304	1.11(0.88–1.40)	0.373
60 ~ 74years	GH/HDL-C	1.19 (1.09–1.30)	< 0.001	1.15 (1.03–1.30)	0.017	1.15 (1.03–1.28)	0.010
≥75years	GH/HDL-C < 4.25	0.81 (0.59–1.13)	0.215	0.64 (0.41–0.98)	0.042	0.64 (0.42–0.98)	0.038
≥75years	GH/HDL-C ≥ 4.25	1.23 (1.09–1.39)	0.001	1.23 (1.10–1.38)	< 0.001	1.23 (1.09–1.39)	< 0.001

Noting: HR, Hazard Ratio; CI, Confidence Interval; GH/HDL-C, Glycated Hemoglobin to High Density Lipoprotein Cholesterol Ratio; HEI, Healthy Eating Index; TC, Total cholesterol; AMI, Acute myocardial infarction; CHD, Coronary heart disease; CHF: Chronic Heart Failure.
Model 1: Crude
Model 2: Adjusted by BMI(< 25 kg/m^2, 25 ~ 30 kg/m^2, ≥ 30 kg/m^2), Gender(Female, Male), Race(Non-Hispanic White and Others), Alcohol(< 12 per life, < 12/year, ≥12/year), Hypertension, Diabetes, CHD, Angina, AMI, Stroke, HEI, TC
Model 3: Adjusted by BMI(< 25 kg/m^2, 25 ~ 30 kg/m^2, ≥30 kg/m^2), Gender(Female, Male), Race(Non-Hispanic White and Others), Alcohol(< 12 per life, < 12/year, ≥12/year), Hypertension, Diabetes, CHD, Angina, AMI, Stroke, HEI, TC, Smoking(never, former and current), CHF, Age(continuous)

ISSN: 1476-511X