Table 1 Baseline patient characteristics

Parameters for the entire cohort, independent of study visit

Sex, female, n (%)

16 (94)

Age, mean ± SD

46 ± 11

Insulin use, n (%)

1 (5)

Prednisolone use, n (%)

1 (5)

Oral contraceptive use, n (%)

8 (47)

Smoked, n (%)

 Never

9 (53)

 Currently

0

 Formerly

8 (47)

 Daily cigarettes (former smokers), mean ± SD

13 ± 7

 Years smoked (former smokers, mean ± SD

14.8 ± 14.0

 Years stopped, mean (min-max)

18 (3–34)

Alcohol, n yes (%)

8 (47)

 Weekly number of alcoholic beverages, mean ± SD

1.1 ± 2.0

Parameters per study visit

Hypothyroidism

(TSH range 59–371 mU/L)

Thyroid hormone supplementation

(TSH range 0.01–2.15 mU/L)

P-value

TSH, mU/L

106 ± 75

0.19 ± 0.51

< 0.001

FT4, pmol/L

2.7 ± 1.5

-

-

Systolic blood pressure, mmHg

124 ± 17

127 ± 17

0.23

Diastolic blood pressure, mmHg

81 ± 8.6

79 ± 12.6

0.43

Pulse, rate/min

68 ± 9.0

77 ± 8.3

0.02

Weight, kg

82.2 ± 15.1

81.0 ± 16.3

0.03

BMI, kg/m²

27.5 ± 4.9

27.1 ± 5.6

0.03

Glucose, mg/dL

89 ± 15

96 ± 25

0.08