Association between triglyceride-glucose index in early pregnancy and risk of preeclampsia: a multicenter retrospective cohort study

Table 2 Risk of primary and secondary outcomes

Outcome	No. of PE (%)	Model I		Model II
Outcome	No. of PE (%)	OR (95% CI)	P-value	Adjust OR (95% CI)	P-value
Primary Outcome
Preeclampsia
TyG Q1	396 (3.81%)	Reference		Reference
TyG Q2	436 (4.18%)	1.10 (0.96, 1.26)	0.1748	0.96 (0.83, 1.13)	0.6525
TyG Q3	627 (6.01%)	1.62 (1.42, 1.84)	< 0.0001	1.23 (1.06, 1.43)	0.0067
TyG Q4	849 (8.14%)	2.24 (1.98, 2.53)	< 0.0001	1.31 (1.11, 1.53)	0.0011
Secondary Outcomes
Preterm birth
TyG Q1	458 (4.45%)	Reference		Reference
TyG Q2	501 (4.84%)	1.09 (0.96. 1.24)	0.1862	1.02 (0.89. 1.18)	0.7328
TyG Q3	595 (5.74%)	1.31 (1.15, 1.48)	< 0.0001	1.08 (0.94.1.24)	0.3003
TyG Q4	752 (7.26%)	1.68 (1.49. 1.89)	< 0.0001	1.18 (1.01, 1.37)	0.0376
Low birth weight
TyG Q1	596 (5.73%)	Reference		Reference
TyG Q2	561 (5.37%)	0.93 (0.83, 1.05)	0.2581	0.94 (0.83, 1.07)	0.3722
TyG Q3	524 (5.03%)	0.87 (0.77, 0.98)	0.0239	0.84 (0.74, 0.97)	0.0147
TyG Q4	527 (5.05%)	0.88 (0.78, 0.99)	0.0302	0.87 (0.75, 1.02)	0.0774

Model I: No covariates were adjusted
Model II: Adjusted for age, pre-pregnancy BMI, systolic blood pressure; diastolic blood pressure, aspirin, depressor, hypertension history, tobacco, alcohol, IVF, alanine transaminase, uric acid, creatinine, total serum cholesterol, test week, adverse pregnancy history, and education levels
PE, preeclampsia; TyG, triglyceride-glucose index; Q, quartile; BMI, body mass index; IVF, in vitro fertilization; OR, odds ratio; CI, confidence interval

ISSN: 1476-511X