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Table 1 Weighted baseline characteristics of the study population

From: Association between the uric acid-to-HDL-cholesterol ratio (UHR) and the risk of cardiovascular disease and dyslipidemia: a population-based study

Characteristic

Total

Quartile 1

Quartile 2

Quartile 3

Quartile 4

P value

Gender (%)

     

 < 0.001

 Male

2256 (37)

153 (8)

380 (27)

673 (42)

1050 (69)

 

 Female

4114 (63)

1438 (92)

1152 (73)

981 (58)

543 (31)

 

Age (years)

49 (34,63)

47 (33,61)

49 (34,63)

50 (35,64)

49 (35,63)

0.165

Ethnic (%)

     

0.07

 Mexican American

1142 (9.6)

324 (10)

284 (10)

281 (8.8)

253 (9.2)

 

 Other Hispanic

540 (5.6)

140 (6.2)

128 (5.5)

143 (5.3)

129 (5.4)

 

 Non-Hispanic White

2365 (62)

542 (60)

525 (58)

612 (62)

686 (65)

 

 Non-Hispanic Black

1476 (14)

366 (14)

396 (16)

405 (14)

309 (11)

 

 Other Race

847 (9.7)

219 (9.8)

199 (10)

213 (9.7)

216 (9.4)

 

Educational level, (%)

     

0.043

 High school or lower

3230 (44)

769 (39)

783 (45)

852 (45)

826 (46)

 

 Above high school

3140 (56)

822 (61)

749 (55)

802 (55)

767 (54)

 

Family income to poverty ratio, n (%)

     

0.499

  ≤ 1.3

2116 (24)

529 (23)

522 (26)

517 (23)

548 (26)

 

 1.3 to 3.5

2587 (39)

644 (38)

606 (38)

709 (40)

628 (40)

 

  ≥ 3.5

1667 (37)

418 (39)

404 (36)

428 (37)

417 (35)

 

Total Cholesterol, mg/dl

188 (163,217)

193 (167,220)

190 (167,217)

185 (158,215)

185 (160,214)

0.001

Triglycerides, mg/dl

105 (73,155)

78 (58,107)

94 (68,130)

114 (80,160)

152 (107,213)

 < 0.001

HDL-C, mg/dl

51 (42,62)

69 (60,78)

56 (50,63)

48 (43,54)

39 (35,44)

 < 0.001

LDL-C, mg/dl

110 (88,135)

105 (85,130)

113 (91,137)

112 (87,138)

110 (88,135)

 < 0.001

BMI, kg/m2

28 (24,34)

25 (22,29)

28 (24,33)

30 (25,35)

31 (28,37)

 < 0.001

Drink, n (%)

     

0.038

 Never

2345 (32)

665 (35)

574 (34)

592 (30)

514 (31)

 

 Former

1615 (23)

346 (19)

386 (23)

420 (24)

463 (26)

 

 Now

2410 (45)

580 (46)

572 (44)

642 (46)

616 (43)

 

Smoke, n (%)

     

 < 0.001

 Never

4399 (68)

1245 (77)

1078 (68%)

1090 (64)

986 (63)

 

 Former

1166 (19)

203 (14)

257 (19)

314 (20)

392 (23)

 

 Now

805 (13)

143 (9.0)

197 (13)

250 (16)

215 (14)

 

Diabetes, n (%)

1369 (16)

178 (7.5)

274 (13)

412 (19)

505 (26)

 < 0.001

Hypertension, n (%)

2938 (41)

538 (29)

676 (39)

838 (43)

886 (53)

 < 0.001

Serum uric acid, mg/dl

5.20(4.30,6.20)

3.90(3.40,4.50)

4,80(4.30,5.40)

5.50(5.00,6.10)

6.70(6.00,7.40)

 < 0.001

CVD, n (%)

559 (7.3)

77 (4.7)

125 (6.3)

144 (7.4)

213 (11)

 < 0.001

CHF, n (%)

216 (2.5)

24 (1.0)

41 (2.0)

58 (2.5)

93 (4.5)

 < 0.001

ASCVD, n (%)

264 (3.3)

33 (1.8)

60 (2.8)

67 (3.0)

104 (5.4)

 < 0.001

Angina, n (%)

171 (2.7)

29 (1.9)

34 (1.6)

42 (2.5)

66 (4.5)

 < 0.001

CHD, n (%)

269 (3.7)

32 (1.9)

60 (3.1)

75 (4.0)

102 (5.6)

 < 0.001

Hyperlipidemia, n (%)

4117 (64)

804 (47)

893 (57)

1095 (67)

1325 (84)

 < 0.001

UHR

10.2 (7.4,13.6)

5.8 (5.0,6.6)

8.6 (7.9,9.2)

11.5(10.7,12.4)

16.5(14.9,19.0)

 < 0.001

  1. Median (IQR) for continuous; n() for categorical, and all estimates accounted for complex survey designs in NHANES
  2. Bold indicates statistical significance
  3. LDL-C Low-density lipoprotein cholesterol, HDL-C High-density lipoprotein cholesterol, BMI Body mass index, CVD Cardiovascular disease, CHF Congestive heart failure, ASCVD Atherosclerotic cardiovascular disease, CHD Congestive heart disease
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Lipids in Health and Disease

ISSN: 1476-511X