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Table 1 Baseline characteristics of the study participants

From: Association between FIB-4 index and lower extremity arterial disease in MASLD patients: a cross-sectional study

Variables

Total

(n = 481)

Fibrosis-4 index

p value

< 1.3 (n = 226)

1.3–2.66 (n = 203)

> 2.66 (n = 52)

Sex, n (%)

    

0.009

Male

245 (50.9)

130 (57.5)

87 (42.9)

28 (53.8)

 

Female

236 (49.1)

96 (42.5)

116 (57.1)

24 (46.2)

 

Age, years

58.4 ± 12.6

50.8 ± 11.2

64.9 ± 9.2

66.1 ± 11.7

< 0.001

BMI, kg/m2

27.3 ± 3.7

27.6 ± 4.1

26.9 ± 3.2

27.2 ± 4.0

0.137

LEAD, n (%)

294 (61.1)

116 (51.3)

133 (65.5)

45 (86.5)

< 0.001

T2DM, n (%)

    

0.272

Non-T2DM

241 (50.1)

121 (53.5)

99 (48.8)

21 (40.4)

 

Prediabetes

105 (21.8)

44 (19.5)

50 (24.6)

11 (21.2)

 

T2DM

135 (28.1)

61 (27)

54 (26.6)

20 (38.5)

 

Hypertension, n (%)

266 (55.3)

115 (50.9)

121 (59.6)

30 (57.7)

0.18

Dyslipidemia, n (%)

97 (20.2)

52 (23)

34 (16.7)

11 (21.2)

0.267

Former/Current smoker

, n (%)

116 (24.1)

66 (29.2)

38 (18.7)

12 (23.1)

0.04

TC, mmol/L

4.5 ± 1.4

4.6 ± 1.2

4.4 ± 1.4

4.6 ± 2.3

0.18

HDL-C, mmol/L

1.1 ± 0.3

1.1 ± 0.3

1.1 ± 0.2

1.1 ± 0.5

0.425

LDL-C, mmol/L

2.6 ± 0.9

2.7 ± 0.8

2.5 ± 0.9

2.7 ± 1.1

0.009

FIB4a

1.3 (1.0, 1.9)

0.9 (0.7, 1.1)

1.6 (1.4, 2.1)

3.5 (3.1, 4.5)

< 0.001

TGa, mmol/L

1.6 (1.2, 2.3)

1.8 (1.3, 2.4)

1.5 (1.1, 2.2)

1.6 (1.0, 2.3)

0.004

Lp(a)a, g/L

0.1 (0.1, 0.2)

0.1 (0.1, 0.2)

0.1 (0.1, 0.2)

0.1 (0.1, 0.2)

0.887

  1. Note: BMI, body mass index; FIB-4, Fibrosis-4 index; LEAD, lower extremity artery disease; T2DM, type 2 diabetes mellitus; TC, Total cholesterol; TG, Triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL, low-density lipoprotein cholesterol; Lp(a), lipoprotein(a); aFIB-4, triglycerides and Lp(a) expressed as median (IQR) and rest are expressed as mean ± SD
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Lipids in Health and Disease

ISSN: 1476-511X