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Fig. 2 | Lipids in Health and Disease

Fig. 2

From: Druggable genome-wide Mendelian randomization identifies therapeutic targets for metabolic dysfunction-associated steatotic liver disease

Fig. 2

Regional Manhattan plot of associations between SNPs and MFGE8 and CD33 locus. (A) rs10520679 was used to proxy serum MFGE8 expression. (B) rs10520679 and its flanking 500 kb region to either side in MASLD. (C) rs1710398 was used to proxy serum CD33 expression. (D) rs1710398 and its flanking 500 kb region to either side in MASLD. MASLD, metabolic dysfunction associated steatotic liver disease; MFGE8, milk fat globule-EGF factor 8; SNP, single-nucleotide polymorphisms

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