Skip to main content

Table 2 Associations of the TyG-BMI, LHR, MHR and NHR with incident type 2 diabetes mellitus according to Cox proportional hazards models

From: Sex differences in associations of metabolic inflammation and insulin resistance with incident type 2 diabetes mellitus: a retrospective cohort of adults with annual health examinations

  

Crude model

Adjusted modela

HR(95% CI)

P

P interaction

HR(95% CI)

P

P interaction

TyG-BMIb

Total

1.09(1.02,1.15)

0.007

0.106

1.09(1.02,1.17)

0.013

0.193

Male

1.16(1.07,1.27)

< 0.001

 

1.14(1.04,1.25)

0.007

 

Female

1.04(0.94,1.16)

0.440

 

1.11(1.00,1.23)

0.060

 

LHR

Total

1.43(1.06,1.92)

0.019

0.026

1.47(1.03,2.09)

0.031

0.034

Male

1.15(0.75,1.77)

0.527

 

1.10(0.68,1.79)

0.697

 

Female

2.38(1.47,3.84)

< 0.001

 

2.39(1.39,4.09)

0.002

 

MHR

Total

4.68(1.27,17.22)

0.020

0.154

6.69(1.47,30.52)

0.014

0.177

Male

3.52(0.56,21.96)

0.178

 

3.36(0.45,25.03)

0.237

 

Female

26.71(3.19,223.68)

0.002

 

21.18(2.02,221.64)

0.011

 

NHR

Total

1.25(1.07,1.45)

0.005

0.302

1.25(1.06,1.49)

0.009

0.356

Male

1.18(0.95,1.47)

0.142

 

1.14(0.90,1.46)

0.281

 

Female

1.38(1.13,1.69)

0.002

 

1.36(1.08,1.70)

0.008

 
  1. Abbreviations: TyG-BMI triglyceride glucose-body mass index, LHR lymphocyte-high density lipoprotein cholesterol ratio, MHR monocyte-high density lipoprotein cholesterol ratio, NHR neutrophil-high density lipoprotein cholesterol ratio
  2. aThe adjusted models were adjusted for sex (male as reference), age, and baseline diagnoses of hypertension and dyslipidaemia
  3. bTyG-BMI was converted to one-tenth of its original value
Back to article page

Lipids in Health and Disease

ISSN: 1476-511X