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Table 4 Predictive performance for CAS, severe CAS and CHD

From: Novel lipid profiles and atherosclerotic cardiovascular disease risk: insights from a latent profile analysis

For CAS

AUC

Sensitivity

Specificity

   TyG

0.633 (0.591, 0.675)

0.690 (0.659, 0.720)

0.518 (0.486, 0.551)

   LDL

0.635 (0.593, 0.677)

0.622 (0.590, 0.654)

0.619 (0.588, 0.651)

   HDL

0.584 (0.541, 0.628)

0.628 (0.596, 0.660)

0.514 (0.481, 0.546)

   TC

0.606 (0.562, 0.649)

0.666 (0.635, 0.697)

0.514 (0.481, 0.546)

   Lp (a)

0.534 (0.490, 0.578)

0.613 (0.581, 0.645)

0.463 (0.431, 0.496)

Lipid Profiles alone

0.877 (0.811, 0.943)

0.744 (0.716, 0.773)

0.899 (0.879, 0.919)

Full model

0.882 (0.860, 0.903)

0.703 (0.673, 0.733)

0.950 (0.935, 0.964)

For severe CAS

   

   TyG

0.703 (0.665, 0.742)

0.715 (0.685, 0.744)

0.640 (0.609, 0.672)

   LDL

0.667 (0.627, 0.708)

0.724 (0.694, 0.753)

0.563 (0.530, 0.595)

   HDL

0.624 (0.584, 0.665)

0.768 (0.740, 0.795)

0.466 (0.433, 0.498)

   TC

0.646 (0.605, 0.687)

0.649 (0.618, 0.680)

0.625 (0.594, 0.657)

   Lp (a)

0.566 (0.524, 0.608)

0.691 (0.661, 0.721)

0.439 (0.407, 0.472)

Lipid Profiles alone

0.912 (0.897, 0.927)

1.000 (1.000, 1.000)

0.806 (0.780, 0.832)

Full model

0.917 (0.899, 0.935)

0.979 (0.969, 0.988)

0.811 (0.785, 0.836)

For CHD

   

   TyG

0.659 (0.623, 0.695)

0.607 (0. 575, 0.639)

0.672 (0.641, 0.703)

   LDL

0.639 (0.602, 0.676)

0.635 (0.604, 0.667)

0.615 (0.583, 0.646)

   HDL

0.595 (0.558, 0.632)

0.691 (0.661, 0.722)

0.482 (0.450, 0.515)

   TC

0.608 (0.571, 0.645)

0.556 (0.524, 0.589)

0.642 (0.611, 0.674)

   Lp (a)

0.546 (0.508, 0.584)

0.653 (0.622, 0.684)

0.439 (0.406, 0.471)

Lipid Profiles alone

0.951 (0.937, 0.965)

0.860 (0.837, 0.882)

0.959 (0.945, 0.972)

Full model

0.957 (0.943, 0.970)

0.849 (0.826, 0.873)

0.960 (0.948, 0.973)