Table 2 Mendelian randomization results of the effect of RC on the risk of AAD, along with tests for heterogeneity and horizontal pleiotropy

AAA

IVW

50

2.08

2.08(1.70–2.56)

2.28E-12

0.65

 < 0.01

MR Egger

1.97

1.97(1.42–2.73

1.87E-04

Weighted mode

1.77

1.77(1.40–2.24)

1.64E-05

Weighted median

1.81

1.81(1.43–2.28)

5.71E-07

Simple mode

2.24

2.24(1.22–4.10)

1.00E-02

TAA

IVW

50

1.08

1.08(0.94–1.23)

2.80E-01

0.96

0.01

MR Egger

1.08

1.08(0.88–1.33)

4.80E-01

Weighted mode

1.25

1.25(1.05–1.49)

2.00E-02

Weighted median

1.28

1.28(1.08–1.52)

0.40E-02

Simple mode

1.07

1.07(0.76–1.51)

6.90E-01

AD

IVW

50

1.24

1.24(0.99–1.56)

6.00E-02

0.75

0.42

MR Egger

1.19

1.19(0.83–1.70)

3.60E-01

Weighted mode

1.52

1.52(1.04–2.23)

4.00E-02

Weighted median

1.51

1.51(1.05–2.16)

3.00E-02

Simple mode

1.24

1.24(0.57–2.70)

5.90E-01