Fig. 7
From: Crosstalk between renin and arachidonic acid (and its metabolites)

Scheme showing local prorenin synthesis in the ovaries, uteroplacental unit and fetal membranes, known stimulators and inhibitors of prorenin synthesis, and possible functions (local and systemic) of prorenin. ATP = adenosine triphosphate; Ca 2 + = extracellular calcium; cAMP = cyclic adenosine monophosphate; hCG = human chorionic gonadotropin; PDE = phosphodiesterase; PDEi = phosphodiesterase inhibitor. PKC = protein kinase C; TNF = tumor necrosis factor; VEGF = vascular endothelial growth factor