Table 2 Associations of the maternal lipid profile in late pregnancy with offspring birth weight (g) in women with and without GDM
Lipid levels and percentile categories | Non-GDM | GDM | ||
|---|---|---|---|---|
β (95% CI) | P value | β (95% CI) | P value | |
TG (mmol/L) | 28.2 (21.9 to 34.5) | < 0.001 | 28.4 (17.8 to 39.1) | < 0.001 |
≤ 10th percentile | Reference | Reference | ||
10th-90th percentile | 64.8 (38.4 to 91.1) | < 0.001 | 78.1 (21.7 to 134.5) | 0.007 |
≥ 90th percentile | 136.9 (100.4 to 173.3) | < 0.001 | 156.2 (87.8 to 224.5) | < 0.001 |
TC (mmol/L) | -6.3 (-12.8 to 0.2) | 0.100 | -19.2 (-31.9 to -6.5) | 0.003 |
≤ 10th percentile | Reference | Reference | ||
10th-90th percentile | -17.9 (-45.3 to 9.4) | 0.198 | -48.3 (-96.9 to 0.3) | 0.051 |
≥ 90th percentile | -17.3 (-53.2 to 18.6) | 0.344 | -66.8 (-136.5 to 2.8) | 0.060 |
HDL (mmol/L) | -79.1 (-102.3 to -55.9) | < 0.001 | -120.7 (-164.8 to -76.6) | < 0.001 |
≤ 10th percentile | Reference | Reference | ||
10th-90th percentile | -51.8 (-80.3 to -23.3) | < 0.001 | -97.9 (-150.5 to -45.3) | < 0.001 |
≥ 90th percentile | -114.3 (-152.0 to -76.6) | < 0.001 | -141.2 (-215.1 to -67.4) | < 0.001 |
LDL (mmol/L) | -9.5 (-18.5 to -0.5) | 0.039 | -22.2 (-40.4 to -4.0) | 0.017 |
≤ 10th percentile | Reference | Reference | ||
10th-90th percentile | -31.6 (-61.1 to -2.0) | 0.036 | -28.2 (-76.2 to 19.9) | 0.250 |
≥ 90th percentile | -35.7 (-73.8 to 2.3) | 0.066 | -87 (-162.5 to -11.5) | 0.024 |