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Table 2 Associations between indicators of lipid and glucose metabolism and hypothyroidism

From: Associations between indicators of lipid and glucose metabolism and hypothyroidism

Indicators

Model 1

Model 2

Model 3

OR

95% CI

P value

OR

95% CI

P value

OR

95% CI

P value

TyG (continuous)

1.65

1.36, 2.02

< 0.001

1.51

1.21, 1.88

< 0.001

1.45

1.12, 1.87

0.004

TyG (quartile)

         

 Q1 [6.66,8.19)

—

—

 

—

—

 

—

—

 

 Q2 [8.19,8.59)

2.26

1.50, 3.40

< 0.001

1.85

1.21, 2.83

0.004

1.87

1.22, 2.87

0.004

 Q3 [8.59,9.01)

2.26

1.50, 3.40

< 0.001

1.84

1.20, 2.83

0.005

1.71

1.10, 2.65

0.017

 Q4 [9.01,11.00]

2.69

1.80, 4.01

< 0.001

2.11

1.38, 3.22

< 0.001

1.95

1.24, 3.07

0.004

 P for trend

  

< 0.001

  

0.002

  

0.020

TG (continuous)

1.00

1.00, 1.01

< 0.001

1.00

1.00, 1.01

< 0.001

1.00

1.00, 1.01

0.001

TG (quartile)

         

 Q1 [14,75)

—

—

 

—

—

 

—

—

 

 Q2 [75,105)

1.40

0.94, 2.09

0.099

1.19

0.79, 1.80

0.410

1.18

0.78, 1.80

0.427

 Q3 [105,152)

1.91

1.31, 2.78

< 0.001

1.60

1.08, 2.36

0.020

1.52

1.02, 2.28

0.041

 Q4 [152,398]

2.12

1.46, 3.07

< 0.001

1.70

1.15, 2.52

0.008

1.62

1.07, 2.45

0.022

 P for trend

  

< 0.001

  

0.003

  

0.010

RC (continuous)

1.02

1.01, 1.03

< 0.001

1.02

1.01, 1.03

< 0.001

1.02

1.01, 1.03

0.001

RC (quartile)

         

 Q1 [3,15)

—

—

 

—

—

 

—

—

 

 Q2 [15,21)

1.48

0.98, 2.22

0.061

1.21

0.79, 1.84

0.380

1.19

0.78, 1.83

0.417

 Q3 [21,30)

1.81

1.23, 2.69

0.003

1.50

0.99, 2.26

0.053

1.44

0.94, 2.18

0.090

 Q4 [30,80]

2.23

1.53, 3.25

< 0.001

1.75

1.17, 2.61

0.006

1.66

1.09, 2.52

0.018

 P for trend

  

< 0.001

  

0.002

  

0.010

TC (continuous)

1.01

1.00, 1.01

0.001

1.00

1.00, 1.00

0.899

1.00

1.00, 1.00

0.851

non-HDL-C (continuous)

1.00

1.00, 1.01

0.003

1.00

1.00, 1.00

0.452

1.00

1.00, 1.00

0.464

HDL-C (continuous)

1.00

1.00, 1.01

0.383

0.99

0.98, 1.00

0.027

0.99

0.98, 1.00

0.140

  1. TyG triglyceride-glucose index, TG triglyceride, RC remnant cholesterol, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, OR odds ratio, CI confidence interval
  2. Model 1: no covariables were adjusted
  3. Model 2: adjusted for gender, age, and race
  4. Model 3: adjusted for gender, age, race, educational level, marital status, PIR, BMI, hypertension, diabetes mellitus, cardiovascular disease, alcohol consumption, and smoking status