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Table 4 The longitudinal study that exploring the associations between cumulative mean HbA1c/HDL-C (2011–2015) and new stroke incidence in 2015–2018

From: Association between the hemoglobin A1c/High-density lipoprotein cholesterol ratio and stroke incidence: a prospective nationwide cohort study in China

Cumulative mean HbA1c/HDL-C

New stroke incidence

OR (95% CI)

P value

Crude Model

 Continuous

1.21(1.12,1.33)

 < 0.0001

Categories

 Tertile1

ref

ref

 Tertile2

1.68(1.25,2.25)

 < 0.001

 Tertile3

1.95(1.46,2.60)

 < 0.0001

 P for trend

 

 < 0.0001

Model 1

 Continuous

1.18(1.08,1.29)

 < 0.001

Categories

 Tertile1

ref

ref

 Tertile2

1.61(1.19,2.18)

0.002

 Tertile3

1.78(1.32,2.41)

 < 0.001

 P for trend

 

 < 0.001

Model 2

 Continuous

1.18(1.07,1.30)

 < 0.001

Categories

 Tertile1

ref

ref

 Tertile2

1.62(1.20,2.19)

0.002

 Tertile3

1.79(1.32,2.42)

 < 0.001

 P for trend

 

 < 0.001

Model 3

 Continuous

1.14(1.01,1.29)

0.04

Categories

 Tertile1

ref

ref

 Tertile2

1.65(1.21,2.24)

0.002

 Tertile3

1.54(1.08,2.19)

0.02

 P for trend

 

0.02

  1. HbA1c Hemoglobin A1c, HDL-C High-density lipoprotein cholesterol, BMI Body mass index, DM Diabetes mellitus, TC Total cholesterol, TG Triglyceride, FBG Fasting blood glucose, UA Uric acid
  2. Crude Model: no covariates were adjusted
  3. Model 1: age, sex, education, residence, marital status, BMI were adjusted
  4. Model 2: age, sex, education, residence, marital status, BMI, smoking, and drinking were adjusted
  5. Model 3: age, sex, education, residence, marital status, BMI, smoking, drinking, hypertension, DM, dyslipidemia, chronic lung disease, heart disease, TC, TG, FBG, UA, and hemoglobin were adjusted
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Lipids in Health and Disease

ISSN: 1476-511X