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Table 2 Baseline population characteristics of the longitudinal study across HbA1c/HDL-C tertiles in 2011

From: Association between the hemoglobin A1c/High-density lipoprotein cholesterol ratio and stroke incidence: a prospective nationwide cohort study in China

Characteristic

Total

(n = 5165)

Tertiles

P value

T1 (1.65,3.88)

(n = 1728)

T2 (3.88,4.81)

(n = 1718)

T3 (4.81,8.97)

(n = 1719)

Age, year

58.35 ± 8.24

58.48 ± 8.31

58.13 ± 8.26

58.43 ± 8.13

0.93

Age, n (%)

    

0.65

 < 60

2942(56.96)

972(56.25)

993(57.80)

977(56.84)

 

 > = 60

2223(43.04)

756(43.75)

725(42.20)

742(43.16)

 

Female, n (%)

2867(55.51)

1012(58.56)

977(56.87)

878(51.08)

 < 0.0001

Education, n (%)

    

 < 0.001

 Primary school or lower

3634(70.36)

1268(73.38)

1206(70.20)

1160(67.48)

 

 Middle school or higher

1531(29.64)

460(26.62)

512(29.80)

559(32.52)

 

Marital status, n (%)

    

 < 0.01

 Married

4667(90.36)

1536(88.89)

1549(90.16)

1582(92.03)

 

 Non-Married

498(9.64)

192(11.11)

169(9.84)

137(7.97)

 

Residence, n (%)

    

 < 0.0001

 Rural area

3509(67.94)

1259(72.86)

1166(67.87)

1084(63.06)

 

 Urban

1656(32.06)

469(27.14)

552(32.13)

635(36.94)

 

BMI, kg/m2

    

 < 0.0001

 < 24

3004(58.16)

1300(75.23)

998(58.09)

706(41.07)

 

 24–28

1745(33.79)

363(21.01)

588(34.23)

794(46.19)

 

 > = 28

416(8.05)

65(3.76)

132(7.68)

219(12.74)

 

Smoking, n (%)

1936(37.48)

610(35.30)

622(36.20)

704(40.95)

 < 0.01

Drinking, n (%)

1692(32.76)

656(37.96)

532(30.97)

504(29.32)

 < 0.0001

Hypertension, n (%)

1999(38.70)

569(32.93)

627(36.50)

803(46.71)

 < 0.0001

DM, n (%)

656(12.70)

107(6.19)

131(7.63)

418(24.32)

 < 0.0001

Dyslipidemia, n (%)

2077(40.21)

360(20.83)

503(29.28)

1214(70.62)

 < 0.0001

Heart disease, n (%)

553(10.71)

145(8.39)

175(10.19)

233(13.55)

 < 0.0001

Chronic lung disease, n (%)

513(9.93)

182(10.53)

169(9.84)

162(9.42)

0.55

New stroke incidence, n (%)

336(6.51)

75(4.34)

122(7.10)

139(8.09)

 < 0.0001

Hemoglobin, g/dL

14.39 ± 2.17

14.10 ± 2.06

14.44 ± 2.17

14.62 ± 2.25

 < 0.0001

TC, mg/dL

193.52 ± 38.01

198.80 ± 35.47

191.33 ± 37.14

190.41 ± 40.70

 < 0.0001

TG, mg/dL

130.58 ± 93.65

92.63 ± 45.51

120.97 ± 65.31

178.33 ± 127.26

 < 0.0001

LDL-C, mg/dL

116.71 ± 34.37

116.71 ± 32.74

119.31 ± 33.07

114.11 ± 36.96

0.01

FBG, mg/dL

108.19 ± 30.92

101.76 ± 17.71

104.18 ± 19.33

118.67 ± 44.92

 < 0.0001

BUN, mg/dL

15.64 ± 4.32

16.07 ± 4.62

15.40 ± 4.12

15.45 ± 4.18

 < 0.0001

Creatinine, mg/dL

0.77 ± 0.18

0.75 ± 0.18

0.76 ± 0.17

0.78 ± 0.19

 < 0.0001

UA, mg/dL

4.36 ± 1.21

4.22 ± 1.16

4.30 ± 1.19

4.56 ± 1.26

 < 0.0001

Cumulative mean HbA1c/HDL-C

4.48 ± 1.18

3.31 ± 0.41

4.32 ± 0.26

5.81 ± 0.89

 < 0.0001

  1. HbA1c Hemoglobin A1c, HDL-C High-density lipoprotein cholesterol, BMI Body mass index, DM Diabetes mellitus, TC Total cholesterol, TG Triglyceride, LDL-C Low-density lipoprotein cholesterol, FBG Fasting blood glucose, BUN Blood urea nitrogen, UA Uric acid