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Table 6 Cut-off between AUC, sensitivity and specificity for indices to detect TD

From: Negative association between 15 obesity- and lipid-related indices and testosterone in adult males: a population based cross-sectional study

Indices

AUC

95%CIs

Cut-off value

Sensitivity

Specificity

Youden’s index

ABSI

 Overall

0.642

0.621—0.664

0.081

77.7%

42.8%

0.205

 Group 1[18,39)

0.673

0.633—0.714

0.078

81.5%

44.8%

0.263

 Group 2[39–59)

0.586

0.546—0.625

0.082

66.4%

47.8%

0.141

 Group 3[59-

0.575

0.538—0.612

0.086

60.9%

52.8%

0.138

BMI

 Overall

0.719

0.697—0.740

28.9

65.0%

66.7%

0.317

 Group 1[18,39)

0.757

0.717—0.797

32

55.5%

85.0%

0.404

 Group 2[39–59)

0.713

0.677—0.749

29

68.0%

64.6%

0.327

 Group 3[59-

0.688

0.652—0.724

29

61.3%

67.9%

0.292

BRI

 Overall

0.747

0.727—0.767

5.024

72.0%

63.4%

0.354

 Group 1[18,39)

0.778

0.741—0.815

4.105

83.2%

60.1%

0.433

 Group 2[39–59)

0.724

0.688—0.759

4.919

73.4%

58.3%

0.317

 Group 3[59-

0.700

0.666—0.735

6.891

42.7%

86.0%

0.288

CI

 Overall

0.725

0.705—0.745

7.598

69.5%

63.0%

0.325

 Group 1[18,39)

0.767

0.729—0.804

7.276

74.0%

66.1%

0.401

 Group 2[39–59)

0.687

0.650—0.725

7.66

60.2%

68.7%

0.289

 Group 3[59-

0.668

0.632—0.704

7.945

61.9%

65.3%

0.272

LAP

 Overall

0.729

0.709—0.749

50.844

66.3%

69.0%

0.353

 Group 1[18,39)

0.772

0.735—0.809

52.081

64.7%

78.4%

0.432

 Group 2[39–59)

0.714

0.679—0.749

46.461

77.9%

57.9%

0.358

 Group 3[59-

0.686

0.651—0.721

50.844

61.3%

67.5%

0.288

METS-IR

 Overall

0.698

0.676—0.719

2.404

66.1%

63.1%

0.291

 Group 1[18,39)

0.730

0.687—0.773

2.49

59.5%

80.2%

0.397

 Group 2[39–59)

0.690

0.654—0.726

2.524

52.0%

76.9%

0.290

 Group 3[59-

0.676

0.640—0.711

2.302

79.1%

45.8%

0.249

METS-VF

 Overall

0.735

0.715—0.755

6.504

76.6%

58.2%

0.348

 Group 1[18,39)

0.776

0.740—0.812

6.073

78.6%

64.3%

0.429

 Group 2[39–59)

0.722

0.686—0.758

6.719

56.6%

76.4%

0.329

 Group 3[59-

0.709

0.675—0.743

7.068

45.4%

83.5%

0.289

TyG

 Overall

0.669

0.646—0.691

8.675

62.4%

64.1%

0.265

 Group 1[18,39)

0.690

0.647—0.733

8.676

57.2%

72.9%

0.302

 Group 2[39–59)

0.654

0.616—0.692

8.706

69.3%

57.4%

0.266

 Group 3[59-

0.641

0.603—0.678

9.054

41.1%

80.8%

0.218

TyG-BMI

 Overall

0.742

0.721—0.762

261.606

62.3%

73.7%

0.360

 Group 1[18,39)

0.776

0.737—0.814

255.036

67.1%

74.9%

0.419

 Group 2[39–59)

0.740

0.705—0.774

257.408

70.5%

66.1%

0.366

 Group 3[59-

0.708

0.673—0.743

261.606

58.3%

74.3%

0.326

TyG-WC

 Overall

0.759

0.739—0.778

8.96

69.7%

69.1%

0.387

 Group 1[18,39)

0.787

0.750—0.824

8.34

76.3%

68.5%

0.448

 Group 2[39–59)

0.742

0.707—0.776

9.003

73.8%

64.0%

0.378

 Group 3[59-

0.718

0.683—0.752

9.111

67.9%

65.3%

0.332

TyG-WHtR

 Overall

0.762

0.743—0.782

5.186

68.4%

69.8%

0.382

 Group 1[18,39)

0.788

0.751—0.824

4.903

70.5%

72.6%

0.431

 Group 2[39–59)

0.748

0.714—0.781

5.186

73.4%

66.1%

0.395

 Group 3[59-

0.719

0.684—0.753

5.704

52.0%

81.0%

0.330

VAI

 Overall

0.666

0.644—0.688

1.389

66.2%

59.1%

0.253

 Group 1[18,39)

0.706

0.664—0.748

1.335

70.5%

62.8%

0.333

 Group 2[39–59)

0.650

0.613—0.688

1.626

63.1%

60.1%

0.233

 Group 3[59-

0.646

0.609—0.682

1.367

63.9%

59.2%

0.232

WC

 Overall

0.742

0.722—0.762

102.5

69.3%

67.6%

0.369

 Group 1[18,39)

0.775

0.737—0.813

94.5

80.9%

60.9%

0.418

 Group 2[39–59)

0.715

0.679—0.752

102.4

69.3%

63.9%

0.332

 Group 3[59-

0.700

0.665—0.735

104

68.5%

61.5%

0.301

WHtR

 Overall

0.747

0.727—0.767

0.582

72.0%

63.2%

0.352

 Group 1[18,39)

0.778

0.741—0.815

0.538

83.2%

59.7%

0.430

 Group 2[39–59)

0.724

0.688—0.759

0.622

52.0%

79.6%

0.316

 Group 3[59-

0.700

0.665—0.735

0.661

42.7%

85.9%

0.286

WWI

 Overall

0.715

0.695—0.735

10.726

78.9%

51.5%

0.304

 Group 1[18,39)

0.759

0.722—0.797

10.532

70.5%

69.0%

0.395

 Group 2[39–59)

0.679

0.641—0.716

10.745

75.4%

49.5%

0.249

 Group 3[59-

0.651

0.615—0.687

11.513

59.6%

63.6%

0.233

  1. Abbreviations: AUC Area under curve, CIs Confidence Intervals, ABSI A body shape index, BMI Body mass index, BRI Body roundness index, CI Conicity index, LAP Lipid accumulation product, METS-IR Metabolic score for insulin resistance, METS-VF Metabolical score for visceral fat, TyG Triglyceride-glucose index, TyG-BMI Triglyceride glucose-body mass index, TyG-WC Triglyceride glucose-waist circumference, TyG-WHtR Triglyceride glucose-waist to height ratio, VAI Visceral adiposity index, WC Waist circumference, WHtR Waist to height ratio, WWI Weight-adjusted-waist index