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Fig. 5 | Lipids in Health and Disease

Fig. 5

From: Exploring the molecular mechanisms of tirzepatide in alleviating metabolic dysfunction-associated fatty liver in mice through integration of metabolomics, lipidomics, and proteomics

Fig. 5

Effects of tirzepatide on the liver proteins in MAFLD mice. PCA score plot of proteins between the HFD and NCD groups (A), and between the HFD + tirzepatide and HFD groups (B). (C) GO enrichment analysis of differentially expressed proteins between the HFD and NCD groups. (D) KEGG pathway enrichment analysis of differentially expressed proteins between the HFD and NCD groups. (E) GO enrichment analysis of differentially expressed proteins between the HFD + tirzepatide and HFD groups. (F) KEGG pathway enrichment analysis of differentially expressed proteins between the HFD + tirzepatide and HFD groups. (G) PPI network of differentially expressed proteins between the HFD + tirzepatide and HFD groups

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