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Fig. 4 | Lipids in Health and Disease

Fig. 4

From: Exploring the molecular mechanisms of tirzepatide in alleviating metabolic dysfunction-associated fatty liver in mice through integration of metabolomics, lipidomics, and proteomics

Fig. 4

Effects of tirzepatide on the liver lipids of mice with MAFLD. (A) Statistical chart of lipid classes. (B) PCA score plot of lipids among the NCD, HFD, HFD + tirzepatide, and QC groups. (C) Heatmap of hierarchical clustering analysis for differential lipids of the NCD, HFD, and HFD + tirzepatide groups. Pie charts showing the lipid classes of differentially expressed lipids between the HFD and NCD groups (D), and between the HFD + tirzepatide and HFD groups (E)

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