Fig. 2

Impact of tirzepatide on liver histology in the MAFLD model. Representative HE-stained liver tissue images (A) and representative lipid deposition images stained with ORO (B). Hepatic lipid accumulation was quantified as the percentage of blank (C) or red-stained areas (D) relative to the entire photomicrograph area. Significant differences were noted, with *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001 compared with the HFD group​​