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Table 1 Prospective studies showing that TyG index predicts incident metabolic syndrome

From: The role of the triglyceride-glucose index as a biomarker of cardio-metabolic syndromes

 

Son et al.

Kang et al.

D’Elia et al.

Year

2022

2023

2024

Country

Korea

Korea

Italy

Participants

N = 6091

N = 3580

N = 440

 

(40–69 yrs)

(40–70 yrs)

50.3 yrs

 

50% Male

47% Male

Male only

Follow up

12 yrs

14 yrs

8 yrs

New MetS diagnosis

38.5%

35.4%

21.6%

TyG Index: ROC-AUC

0.65 (0.64–0.66)

0.85 (0.84–0.87)

0.69 (0.63–0.75)

Other Comments

ROC-AUC for TyG index was significantly higher than HOMA-IR ,0.56

ROC-AUC for TyG index was significantly higher than HOMA-IR ,0.70

ROC-AUC for TyG index was not significantly different from HOMA-IR,0.62

  

5 SNPs were not additive to TyG index ROC-AUC

 
  1. Confidence Intervals in parenthesis ( )
  2. SNP-single-nucleotide polymorphisms