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Table 8 Multivariable logistic regression models of LHR with IR and MetS. (we excluded participants with missing covariable data)

From: Association between lymphocyte to high-density lipoprotein cholesterol ratio and insulin resistance and metabolic syndrome in US adults: results from NHANES 2007–2018

 

Model 1

 

Model 2

 

Model 3

 
 

OR (95% CI)

p-value

OR (95% CI)

p-value

OR (95% CI)

p-value

IR

      

LHR quartile

      

Q1 (0.004, 0.027)

Reference

 

Reference

 

Reference

 

Q2 (0.027, 0.038)

1.89 (1.60, 2.22)

< 0.001

2.18 (1.83, 2.58)

< 0.001

1.50 (1.23, 1.83)

< 0.001

Q3 (0.038, 0.050)

3.63 (3.10, 4.26)

< 0.001

4.54 (3.84, 5.37)

< 0.001

2.36 (1.94, 2.87)

< 0.001

Q4 (≥ 0.050)

5.63 (4.75, 6.67)

< 0.001

7.44 (6.15, 9.00)

< 0.001

3.33 (2.65, 4.19)

< 0.001

p for trend

 

< 0.001

 

< 0.001

 

< 0.001

MetS

      

LHR quartile

      

Q1 (0.004, 0.027)

Reference

 

Reference

 

Reference

 

Q2 (0.027, 0.038)

1.67 (1.33, 2.11)

< 0.001

2.69 (2.08, 3.48)

< 0.001

1.99 (1.46, 2.72)

< 0.001

Q3 (0.038, 0.050)

3.00 (2.44, 3.70)

< 0.001

6.62 (5.22, 8.40)

< 0.001

3.84 (2.94, 5.02)

< 0.001

Q4 (≥ 0.050)

5.50 (4.34, 6.98)

< 0.001

17.26 (13.08, 22.79)

< 0.001

11.18 (8.15, 15.33)

< 0.001

p for trend

 

< 0.001

 

< 0.001

 

< 0.001

  1. Note
  2. Model 1: No covariables were adjusted
  3. Model 2: Age, sex, race, educational level, poverty income ratio, and marital status were adjusted
  4. Model 3: Age, sex, race, educational level, poverty income ratio, marital status, daily energy intake, smoking status, alcohol status, physical activity, hypertension, diabetes mellitus, cardiovascular disease, body mass index, alanine aminotransferase, aspartate aminotransferase, creatinine, uric acid, blood urea nitrogen, low-density lipoprotein cholesterol, monocyte count, and neutrophils count were adjusted
  5. LHR: lymphocyte to high-density lipoprotein cholesterol ratio; IR: insulin resistance; MetS: metabolic syndrome; OR: odds ratio; 95% CI: 95% confidence interval; Q1: quartile 1; Q2: quartile 2; Q3: quartile 3; Q4: quartile 4