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Table 1 Clinical characteristics of participants

From: Mediating role of triglyceride-glucose index and its derivatives in the relationship between central obesity and Hashimoto thyroiditis in type 2 diabetes

Characteristics

Control group

(n = 387, 36.1%)

HT group

(n = 684, 63.9%)

P Value

Age (years)

62.27 ± 7.41

62.04 ± 7.92

0.638

Sex-male

215(55.6%)

355(51.9%)

0.249

Married-yes

363(93.8%)

597(87.3%)

< 0.001*

Current smoking-yes

123(31.8%)

214(31.30%)

0.260

Current drinking-yes

88(22.7%)

203(29.7%)

0.023*

Education (years)

10.74 ± 3.27

10.53 ± 2.72

0.295

Duration of diabetes (years)

7(2,15)

7(1,14)

0.165

SBP (mmHg)

131.73 ± 15.85

133.71 ± 12.06

0.033*

DBP (mmHg)

79.23 ± 8.83

79.41 ± 8.63

0.753

Regular exercise-yes

209(54.0%)

554(81.4%)

0.956

Diabetic dietary pattern-yes

276(71.3%)

434(63.8%)

0.004*

Hypertension-yes

263(68%)

465(68%)

0.994

Dyslipidemia-yes

211(54.5%)

361(52.9%)

0.599

Take lipid-lowering drugs-yes

40(10.3%)

77(11%)

0.773

Take hypoglycemic drugs-yes

364(94.1%)

622(90.9%)

0.069

FPG (mmol/L)

8.61 ± 2.83

8.54 ± 3.22

0.742

HbA1C (%)

8.93 ± 1.99

8.83 ± 2.11

0.442

TC (mmol/l)

4.74(4.09,5.53)

4.83(4.14,5.58)

0.429

TG (mmol/l)

1.63(1.16,2.44)

1.52(1.12,2.18)

0.112

HDL-C (mmol/L)

1.20 ± 0.30

1.44 ± 6.73

0.499

LDL-C (mmol/L)

3.11 ± 0.83

2.99 ± 0.87

0.024*

UA (ÎĽmol/L)

294.86 ± 82.33

298.33 ± 83.18

0.511

UREA/CREA

22.04 ± 7.05

23.61 ± 11.22

0.013*

ALT (U/L)

19.4(13.7,30.5)

18.2(13.44,27.08)

0.164

AST (U/L)

16(13.1,20.9)

18.4(14.3,2.24)

< 0.001*

Insulin (mU/L)

14.92 ± 18.27

14.25 ± 14.97

0.603

TSH (ÎĽIU/mL)

1.79 ± 0.89

2.02 ± 0.98

< 0.001*

HOMA-IR

5.86 ± 6.98

5.69 ± 5.95

0.729

BMI (kg/m2)

25.77 ± 3.55

26.04 ± 3.50

0.229

WC (cm)

89.10 ± 10.16

93.17 ± 9.58

< 0.001*

WHtR

0.54 ± 0.06

0.56 ± 0.06

< 0.001*

WHR

0.92 ± 0.07

0.95 ± 0.07

< 0.001*

LAP

44.77(27.14,70.00)

48.72(31.50,76.23)

0.008*

VFA

100.71 ± 29.55

104.80 ± 29.14

0.064

TyG

9.32 ± 0.73

9.26 ± 0.77

0.205

TyG-BMI

240.51 ± 39.34

241.72 ± 41.52

0.640

TyG-WC

831.26 ± 118.03

864.47 ± 125.76

< 0.001*

TyG-WHtR

5.00 ± 0.69

5.21 ± 0.74

< 0.001*

TyG-WHR

8.56 ± 0.94

8.85 ± 1.03

< 0.001*

  1. Data are presented as means ± standard deviations or medians (interquartile ranges) for continuous data and numbers (%) for categorical data
  2. Abbreviation: HT Hashimoto thyroiditis, SBP systolic blood pressure, DBP diastolic blood pressure, FPG fasting plasma glucose, HbA1c hemoglobin A1c, TC total cholesterol, TG triglycerides, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, UA uric acid, UREA/CREA urea nitrogen related to creatinine, ALT alanine aminotransferase, AST aspartate aminotransferase, TSH thyroid stimulating hormone, HOMA-IR homeostasis model assessment of IR, BMI body mass index, WC waist circumference, WHtR waist to height ratio, WHR waist to hip ratio, LAP lipid accumulation product, VFA visceral fat area, TyG triglyceride glucose index
  3. *P <0.05