Fig. 4

Nonlinear analysis of IR and obesity indices with HT risk in T2DM patients. Nonlinear associations obesity, triglyceride-glucose and its derivative indices with Hashimoto thyroiditis risk in T2DM patients were explored using restricted cubic spline (RCS) models and fitted with smooth curves. A BMI, body mass index; B WC, waist circumference; C WHtR, waist-to-height; D WHR, waist to hip ratio; E LAP, lipid accumulation product; F VFA, visceral fat area; G TyG index, triglyceride glucose index; H TyG-BMI = TyG × BMI; I TyG-WC = TyG × WC; J TyG-WHR = TyG × WHR; K TyG-WHtR = TyG × WHtR. The models were adjusted for age, sex, years of education, married, current smoking, current drinking, hemoglobin A1c, duration of diabetes, dyslipidemia, hypertension, take lipid-lowering drugs, regular exercise, diabetic dietary pattern, uric acid, urea nitrogen related to creatinine, alanine aminotransferase, aspartate aminotransferase, thyroid stimulating hormone, homeostasis model assessment of IR.^* P < 0.05