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Table 2 Levels of Klotho in Relation to CKM Stage 0 to 4

From: Association of serum Klotho with the severity and mortality among adults with cardiovascular-kidney-metabolic syndrome

 

Model1

Model2

Model3

OR (95%CI)

P

OR (95%CI)

P

OR (95%CI)

P

Two-piecewise logistic regression model (Infection point = 801)

Serum klotho<801

0.74(0.64, 0.85)

< 0.001

0.78(0.68, 0.90)

< 0.001

0.82(0.70, 0.96)

< 0.001

Serum klotho ≥ 801

0.91(0.87, 0.94)

< 0.001

0.90(0.86, 0.93)

< 0.001

0.94(0.89, 0.99)

0.035

Binary Variable (Cut-off point = 722)

Serum klotho ≥ 722

Ref

 

Ref

 

Ref

 

Serum klotho<722

1.23(1.14, 1.32)

< 0.001

1.19(1.11, 1.28)

< 0.001

1.20(1.11, 1.30)

< 0.001

  1. Abbreviations: OR, odds ratio; CI, confidence interval. Adjusted Mode: Model 1 (unadjusted), Model 2 (adjusted for sex, age, and race), and Model 3 (further adjusted for sex, age, race, education, PIR, BMI, smoking, alcohol consumption, hypertension, and diabetes). Bold indicates P value < 0.05