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Fig. 4 | Lipids in Health and Disease

Fig. 4

From: Ergothioneine ameliorates metabolic dysfunction-Associated Steatotic Liver Disease (MASLD) by enhancing autophagy, inhibiting oxidative damage and inflammation

Fig. 4

Analyses of transcriptomic differences ergothioneine-treated AML12 cells. (A) Principal component analysis (PCA) of RNA-seq in AML12. (B-E) Difference analysis of PA + EGT vs. PA sequencing results. (B) Cluster analysis. (C) Volcano plots. GO (D) and KEGG (E) enrichment analysis. (F-H) Heatmap of GSEA analysis. Heatmap of autophagy (F), apoptosis (G) and oxidative stress (H) related gene expression profiles. C: Ctrl, P: PA, E: PA + EGT, n = 3

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