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Table 2 Association between homocysteine and cardiometabolic multimorbidity in different models (Association of Plasma Homocysteine with Cardiometabolic Multimorbidity: a cross-sectional study in Northwest China, 2018–2020)

From: Association of plasma homocysteine with cardiometabolic multimorbidity: a cross-sectional study in northwest China

Presence of CMM

Events (%)

Crude Model

Model 1

Model 2

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

having at least 2 diseases

       

Hcy

 

1.008 (1.005, 1.011)

< 0.001

1.006 (1.002, 1.009)

0.001

1.005 (1.002, 1.009)

0.003

Quartiles

       

Q1

494 (10.9)

Reference

 

Reference

 

Reference

 

Q2

625 (13.8)

1.308 (1.153, 1.483)

< 0.001

1.178 (1.034, 1.342)

0.014

1.161 (1.018, 1.323)

0.026

Q3

665 (14.7)

1.406 (1.241, 1.592)

< 0.001

1.164 (1.022, 1.325)

0.022

1.132 (0.994, 1.290)

0.062

Q4

712 (15.7)

1.524 (1.348, 1.723)

< 0.001

1.236 (1.087, 1.406)

0.001

1.203 (1.056, 1.370)

0.005

having at least 3 diseases

       

Hcy

 

1.007 (0.999, 1.014)

0.067

1.003 (0.995, 1.012)

0.407

1.002 (0.994, 1.011)

0.582

Quartiles

       

Q1

75 (1.7)

Reference

 

Reference

 

Reference

 

Q2

101 (2.2)

1.355 (1.002, 1.831)

0.049

1.125 (0.829, 1.528)

0.449

1.101 (0.810, 1.495)

0.540

Q3

99 (2.2)

1.327 (0.981, 1.797)

0.067

0.979 (0.719, 1.334)

0.894

0.921 (0.674, 1.258)

0.605

Q4

111 (2.4)

1.492 (1.110, 2.006)

0.008

1.081 (0.797, 1.465)

0.618

1.020 (0.750, 1.387)

0.899

  1. Bold P value represent < 0.05. Crude Model was not adjusted for any variables; Model 1 was adjusted for age, sex, BMI, education, physical activity, smoking, and alcohol drinking; Model 2 was adjusted for TC, TG, HDL-C and LDL-C based on Model 1. Hcy, homocysteine (µmol/L); OR, Odds ratio; CI Confidence interval; CMM, cardiometabolic multimorbidity