Table 1 Baseline characteristics of study patients with and without CVE
Variables | Total (n = 1305) | Without CVE (n = 1207) | With CVE (n = 98) | P value |
|---|---|---|---|---|
Demographics | ||||
Age, years | 64.92 ± 7.28 | 64.85 ± 7.26 | 65.79 ± 7.60 | 0.222 |
BMI, kg/m2 | 25.44 ± 3.30 | 25.41 ± 3.31 | 25.87 ± 3.16 | 0.208 |
SBP, mmHg | 133.08 ± 17.75 | 132.60 ± 17.35 | 139.06 ± 21.28 | 0.001 |
DBP, mmHg | 74.98 ± 10.69 | 74.90 ± 10.56 | 75.94 ± 12.22 | 0.364 |
Current smoking, n (%) | 46 (3.5) | 42 (3.5) | 4 (4.1) | 0.979 |
Previous smoking, n (%) | 21 (1.6) | 20 (1.7) | 1 (1.0) | 0.949 |
Current drinking, n (%) | 14 (1.1) | 14 (1.2) | 0 (0.0) | 0.574 |
Previous drinking, n (%) | 3 (0.2) | 2 (0.2) | 1 (1.0) | 0.547 |
Family history of CVD, n (%) | 94 (7.2) | 87 (7.2) | 7 (7.1) | 1.000 |
Medical histories, n (%) | ||||
Hypertension | 915 (70.1) | 828 (68.6) | 87 (88.8) | < 0.001 |
Hyperlipemia | 912 (69.9) | 835 (69.2) | 77 (78.6) | 0.067 |
T2DM | 455 (34.9) | 400 (33.1) | 55 (56.1) | < 0.001 |
Previous MI | 109 (8.4) | 100 (8.3) | 9 (9.2) | 0.905 |
Previous PCI | 293 (22.5) | 261 (21.6) | 32 (32.7) | 0.017 |
Previous stroke | 65 (5.0) | 60 (5.0) | 5 (5.1) | 1.000 |
Laboratory results | ||||
TG, mmol/L | 1.42 [1.04, 1.96] | 1.39 [1.03, 1.93] | 1.65 [1.17, 2.24] | 0.001 |
TC, mmol/L | 4.28 [3.67, 5.03] | 4.27 [3.67, 5.04] | 4.30 [3.70, 4.87] | 0.758 |
HDL-C, mmol/L | 1.17 [1.02, 1.36] | 1.17 [1.03, 1.37] | 1.05 [0.94, 1.25] | < 0.001 |
LDL-C, mmol/L | 2.46 [1.94, 3.09] | 2.46 [1.93, 3.11] | 2.50 [2.06, 3.07] | 0.800 |
LVEF, % | 65.00 [60.00, 68.00] | 65.00 [60.00, 68.00] | 63.00 [59.00, 66.00] | 0.010 |
eGFR, mL/min/1.73 m2 | 92.19 [84.15, 98.32] | 92.20 [84.54, 98.27] | 91.75 [78.79, 98.66] | 0.305 |
Cr, mmol/L | 57.40 [50.90, 65.50] | 57.50 [50.90, 65.05] | 57.35 [51.68, 69.52] | 0.332 |
AIP | 0.08 [-0.09, 0.25] | 0.08 [-0.10, 0.24] | 0.19 [0.02, 0.37] | < 0.001 |
GA, n% | 15.40 [14.10, 18.00] | 15.40 [14.00, 17.70] | 17.75 [14.75, 21.85] | < 0.001 |
hs-CRP, mg/L | 1.42 [0.58, 3.49] | 1.38 [0.57, 3.36] | 2.12 [1.04, 4.25] | 0.002 |
FBG, mmol/L | 5.77 [5.16, 7.31] | 5.73 [5.15, 7.18] | 6.96 [5.44, 9.81] | < 0.001 |
Uric acid, µmol/L | 302.30 [253.40, 353.10] | 301.40 [252.30, 352.75] | 313.40 [271.58, 364.10] | 0.194 |
HbA1c, % | 6.20 [5.80, 7.10] | 6.20 [5.70, 7.00] | 7.50 [6.25, 8.55] | < 0.001 |
Diagnosis on admission, n (%) | ||||
UAP | 1140 (87.4) | 1061 (87.9) | 79 (80.6) | 0.054 |
NSTEMI | 81 (6.2) | 70 (5.8) | 11 (11.2) | 0.054 |
STEMI | 84 (6.4) | 76 (6.3) | 8 (8.2) | 0.610 |
Medications, n (%) | ||||
DAPT | 1304 (99.9) | 1206 (99.9) | 98 (100.0) | 1.000 |
Statin | 1293 (99.1) | 1195 (99.0) | 98 (100.0) | 0.659 |
β-Blocker | 820 (62.8) | 749 (62.1) | 71 (72.4) | 0.052 |
ACEI/ARB | 612 (46.9) | 559 (46.3) | 53 (54.1) | 0.169 |
CCB | 483 (37.0) | 430 (35.6) | 53 (54.1) | < 0.001 |
Antidiabetic drugs | ||||
Insulin | 131 (10.0) | 113 (9.4) | 18 (18.4) | 0.007 |
OAD | 302 (23.1) | 263 (21.8) | 39 (39.8) | < 0.001 |
Angiographic data | ||||
LM disease, n (%) | 67 (5.1) | 57 (4.7) | 10 (10.2) | 0.033 |
One-vessel disease, n (%) | 454 (34.8) | 431 (35.7) | 23 (23.5) | 0.019 |
Two-vessel disease, n (%) | 471 (36.1) | 430 (35.6) | 41 (41.8) | 0.262 |
Three-vessel disease, n (%) | 380 (29.1) | 346 (28.7) | 34 (34.7) | 0.251 |
CTO disease, n (%) | 225 (17.2) | 203 (16.8) | 22 (22.4) | 0.201 |
Diffuse lesion, n (%) | 478 (36.7) | 434 (36.0) | 44 (44.9) | 0.099 |
Bifurcation lesion, n (%) | 119 (9.1) | 108 (9.0) | 11 (11.2) | 0.570 |
ISR disease, n (%) | 94 (7.2) | 80 (6.6) | 14 (14.3) | 0.009 |
SYNTAX score | 11.00 [7.00, 16.00] | 11.00 [7.00, 15.00] | 13.00 [9.25, 17.88] | 0.005 |
Procedural results | ||||
Target vessel territory, n (%) | ||||
LM | 36 (2.8) | 31 (2.6) | 5 (5.1) | 0.249 |
LAD | 671 (51.4) | 629 (52.1) | 42 (42.9) | 0.097 |
LCX | 234 (17.9) | 215 (17.8) | 19 (19.4) | 0.800 |
RCA | 423 (32.4) | 388 (32.1) | 35 (35.7) | 0.539 |
DES implantation, n (%) | 1262 (96.7) | 1173 (97.2) | 89 (90.8) | 0.002 |
DCB use, n (%) | 55 (4.2) | 46 (3.8) | 9 (9.2) | 0.022 |
IABP, n (%) | 9 (0.7) | 9 (0.7) | 0 (0.0) | 0.823 |
IVUS, n (%) | 8 (0.6) | 8 (0.7) | 0 (0.0) | 0.892 |
OCT, n (%) | 9 (0.7) | 9 (0.7) | 0 (0.0) | 0.823 |
Complete revascularization, n (%) | 503 (38.5) | 479 (39.7) | 24 (24.5) | 0.004 |
Number of stents | 1.00 [1.00, 2.00] | 1.00 [1.00, 2.00] | 1.00 [1.00, 2.00] | 0.560 |
Diameter of stents, mm | 2.75 [2.50, 3.00] | 2.75 [2.50, 3.00] | 2.50 [2.44, 3.00] | 0.049 |
Length of stents, mm | 23.00 [16.00, 30.00] | 23.00 [16.00, 30.00] | 23.00 [14.00, 32.00] | 0.970 |