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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: Heart-healthy diets including phytostanol ester consumption to reduce the risk of atherosclerotic cardiovascular diseases. A clinical review

Fig. 1

Simplified scheme of the absorption of cholesterol, phytosterols, and phytostanols

Footnote:

Niemann–Pick C1-Like 1 transporter takes up cholesterol, phytosterols, and phytostanols into the enterocyte, but about half of the cholesterol and most of the phytosterols, and phytostanols in particular, are driven back to the intestinal lumen via the adenosine triphosphate-binding cassette (ABC) transporters G5 and G8. Eventually, approximately 50–60% of the cholesterol, 0.5–2% of the phytosterols, and 0.04–0.15% of the phytostanols are absorbed into the body [26]

Abbreviations: ABCG5/8 = adenosine triphosphate-binding cassette (ABC) transporters G5 and G8, apoB48 = apoprotein B48, CHOL = cholesterol, NPC1L1 = Niemann–Pick C1-Like 1 transporter, PS = phytosterols and phytostanols, TG = triglycerides

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Lipids in Health and Disease

ISSN: 1476-511X