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Table 4 Stratified analysis of the correlation between lipid accumulation product(LAP), visceral adiposity index (VAI), atherogenic index of plasma (AIP), and diabetic retinopathy (DR) in adults in the NHANES 2005–2008

From: Association of diabetic retinopathy with plasma atherosclerotic index, visceral obesity index, and lipid accumulation products: NHANES 2005–2008

Subgroup

OR(95%CI),P-value

P interaction

OR(95%CI),P-value

P interaction

OR(95%CI),P-value

P interaction

 

lipid accumulation product(LAP)

 

visceral adiposity index(VAI)

 

atherogenic index of plasma(AIP)

 

AGE

 

0.778

 

0.5861

 

0.9544

< 60

1.00 (1.00, 1.01) 0.0260

 

1.06 (0.98, 1.16) 0.1604

 

1.83 (0.80, 4.21) 0.1537

 

≥ 60

1.00 (1.00, 1.01) 0.0057

 

1.10 (1.00, 1.20) 0.0469

 

1.77 (0.77, 4.07) 0.1755

 

Gender

 

0.5017

 

0.1092

 

0.0689

Male

1.00 (1.00, 1.01) 0.0014

 

1.12 (1.04, 1.21)0.0037

 

2.82 (1.29, 6.16)0.0095

 

Female

1.00 (1.00, 1.01) 0.0895

 

1.00 (0.88, 1.13)0.9539

 

0.86 (0.31, 2.38)0.7682

 

Race

 

0.3614

 

0.9088

 

0.9574

Mexican American

1.01 (1.00, 1.01) 0.0082

 

1.11 (0.99, 1.24) 0.0725

 

2.67 (0.78, 9.12) 0.1174

 

Other Hispanic

1.01 (1.00, 1.02) 0.0142

 

1.04 (0.78, 1.39) 0.7913

 

1.80 (0.22, 14.42) 0.5802

 

Non-Hispanic White

1.00 (1.00, 1.01) 0.0426

 

1.04 (0.92, 1.19) 0.4984

 

1.40 (0.52, 3.80) 0.5077

 

Non-Hispanic Black

1.00 (1.00, 1.01) 0.7152

 

1.13 (0.97, 1.30) 0.1160

 

1.94 (0.43, 8.71) 0.3878

 

Other Race

1.00 (0.98, 1.02) 0.8883

 

0.98 (0.63, 1.52) 0.9231

 

2.13 (0.05, 90.04) 0.6924

 

Education Level

 

0.4551

 

0.8002

 

0.3853

Less Than 9th Grade

1.00 (0.99, 1.01) 0.7552

 

1.04 (0.78, 1.39) 0.7648

 

0.36 (0.02, 5.66) 0.4675

 

9-11th Grade

1.01 (1.00, 1.02) 0.0193

 

1.12 (0.92, 1.36) 0.2446

 

4.65 (0.67, 32.49) 0.1210

 

High School Grad

1.00 (1.00, 1.01) 0.4437

 

0.98 (0.78, 1.23) 0.8628

 

1.88 (0.28, 12.72) 0.5156

 

Some College or AA degree

1.00 (1.00, 1.01) 0.1350

 

1.19 (1.01, 1.41) 0.0389

 

6.67 (1.06, 41.92) 0.0431

 

College Graduate or above

1.01 (1.00, 1.02) 0.2678

 

1.15 (0.90, 1.46) 0.2780

 

1.43 (0.17, 12.01) 0.7409

 

Marital status

 

0.4482

 

0.5603

 

0.6869

Married

1.01 (1.00, 1.01) 0.0019

 

1.12 (1.03, 1.23) 0.0115

 

2.31 (1.00, 5.31) 0.0499

 

Widowed

1.00 (0.99, 1.01) 0.5223

 

0.88 (0.65, 1.19) 0.3934

 

0.86 (0.19, 3.84) 0.8439

 

Divorced

1.01 (1.00, 1.01) 0.0870

 

1.11 (0.93, 1.31) 0.2482

 

3.25 (0.82, 12.95) 0.0946

 

Separated

1.01 (0.99, 1.03) 0.3077

 

1.15 (0.69, 1.94) 0.5864

 

7.74 (0.42, 142.52) 0.1683

 

Never married

1.00 (0.99, 1.01) 0.9572

 

0.97 (0.79, 1.19) 0.7853

 

1.23 (0.31, 4.79) 0.7681

 

Living with partner

1.00 (0.99, 1.01) 0.7018

 

0.99 (0.67, 1.46) 0.9554

 

1.13 (0.14, 9.05) 0.9114

 

Poverty-to-income ratio

 

0.3584

 

0.0549

 

0.3153

< 1.3

1.01 (1.00, 1.01) 0.0034

 

1.20 (1.07, 1.34) 0.0020

 

2.81 (1.07, 7.38) 0.0355

 

1.3–2.5

1.00 (1.00, 1.01) 0.0127

 

1.12 (1.00, 1.26) 0.0537

 

2.62 (0.94, 7.33) 0.0655

 

≥ 2.5

1.00 (1.00, 1.01) 0.3164

 

0.98 (0.87, 1.12) 0.7877

 

1.08 (0.39, 3.00) 0.8868

 

Smoke

 

0.8543

 

0.8097

 

0.946

YES

1.00 (1.00, 1.01) 0.0719

 

1.13 (0.95, 1.35) 0.1657

 

1.78 (0.32, 9.98) 0.5140

 

NO

1.00 (1.00, 1.01) 0.3736

 

1.12 (0.94, 1.34) 0.2185

 

2.51 (0.52, 12.19) 0.2537

 

Alcohol drinking

 

0.6199

 

0.3363

 

0.7461

YES

1.01 (0.99, 1.02) 0.3024

 

0.99 (0.70, 1.39) 0.9437

 

2.01 (0.14, 28.65) 0.6071

 

NO

1.00 (0.99, 1.01) 0.9111

 

0.87 (0.63, 1.21) 0.4236

 

0.76 (0.06, 9.31) 0.8281

 

Hypertension

 

0.3877

 

0.6113

 

0.7047

YES

1.01 (1.00, 1.01) 0.0243

 

1.12 (0.96, 1.31) 0.1538

 

2.76 (0.67, 11.40) 0.1606

 

NO

1.00 (1.00, 1.01) 0.1369

 

1.05 (0.96, 1.15) 0.3148

 

1.43 (0.55, 3.70) 0.4581

 

Taking insulin

 

0.2210

 

0.8922

 

0.7555

YES

1.01 (1.00, 1.03) 0.0714

 

1.12 (0.75, 1.66) 0.5739

 

2.66 (0.22, 31.96) 0.4406

 

NO

1.00 (1.00, 1.01) < 0.0001

 

1.09 (1.04, 1.15) 0.0009

 

1.79 (1.22, 2.61) 0.0026

 

Take diabetic pills

 

0.7546

 

0.5424

 

0.7819

YES

1.01 (1.00, 1.01) 0.0720

 

1.18 (0.98, 1.42) 0.0885

 

2.51 (0.50, 12.64) 0.2645

 

NO

1.00 (0.99, 1.01) 0.6098

 

0.96 (0.68, 1.35) 0.8077

 

0.96 (0.11, 8.03) 0.9679

 
  1. The results show that the subgroup analysis was adjusted for all presented covariates except the effect modifier
  2. Stratified analysis were analyzed using generalized linear models (GLMs) with interaction terms
  3. Abbreviations: 95% CI, 95% confidence interval; OR, odds ratio
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Lipids in Health and Disease

ISSN: 1476-511X