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Table 2 Participant characteristics classified by FT3/FT4 tertiles

From: Increased thyroid hormone sensitivity is correlated with visceral obesity in patients with type 2 diabetes

 

T 1

T 2

T 3

P value

 

0.17–0.27

0.27–0.31

0.31–0.43

 

N

250

250

250

 

Age (year)

50.90 ± 11.76

52.50 ± 10.89

51.22 ± 10.51

0.233

Male, n (%)

156 (62.40)

184 (73.60)

200 (80.00)

< 0.001

Duration of diabetes (month)

94.70 ± 90.70

98.53 ± 82.96

102.19 ± 85.32

0.642

DBP (mmHg)

76.57 ± 10.44

78.89 ± 11.98

79.08 ± 10.17

0.017

SBP (mmHg)

126.99 ± 16.86

130.34 ± 17.07

130.94 ± 16.84

0.020

BMI (kg/m2)

25.88 ± 3.27

28.16 ± 21.40

27.85 ± 11.13

0.146

Waist circumference (cm)

93.69 ± 9.64

97.06 ± 9.24

96.89 ± 8.33

< 0.001

FPG (mmol/ L)

9.12 ± 3.79

8.33 ± 2.67

8.17 ± 3.06

0.002

HbA1C (%)

9.62 ± 2.37

8.74 ± 1.95

8.42 ± 1.76

< 0.001

Uric acid (umol/ L)

324.87 ± 86.88

346.54 ± 87.52

340.55 ± 83.00

0.020

Triglyceride (mmol/l)

1.78 (1.21, 2.48)

1.95 (1.35, 3.22)

1.91 (1.38, 2.92)

0.022

HDL cholesterol (mmol/ L)

1.16 ± 0.30

1.11 ± 0.32

1.09 ± 0.24

0.024

LDL cholesterol (mmol/ L)

2.95 ± 0.87

2.77 ± 0.79

2.80 ± 0.84

0.052

Total cholesterol (mmol/ L)

4.94 ± 1.31

4.73 ± 1.15

4.68 ± 1.11

0.048

FT4 (pmol/L)

17.59 ± 2.15

16.34 ± 1.99

14.65 ± 1.58

< 0.001

TSH (mIU/L)

1.90 (1.24, 2.57)

2.05 (1.40, 2.70)

2.04 (1.51, 2.79)

0.045

VFA (cm2)

98.94 ± 38.59

114.71 ± 39.88

114.75 ± 37.33

< 0.001

SFA (cm2)

186.65 ± 63.98

201.83 ± 61.52

201.81 ± 60.40

0.007

Smoking, n (%)

65 (26.21)

80 (32.00)

95 (38.31)

0.016

Drinking, n (%)

31 (12.55)

64 (25.81)

62 (24.80)

< 0.001

Hypertension, n (%)

89 (35.60)

91 (36.40)

102 (40.80)

0.434

Dyslipidemia, n (%)

101 (40.40)

106 (42.40)

111 (44.40)

0.664

Antihypertensive agents, n (%)

76 (30.40)

81 (32.40)

98 (39.20)

0.093

Lipid lowering agents, n (%)

55 (22.00)

68 (27.31)

74 (29.60)

0.141

Metformin therapy, n (%)

78 (34.21)

93 (40.09)

66 (31.13)

0.397

GLP-1 RA therapy, n (%)

3 (1.32)

3 (1.32)

3 (1.32)

0.703

  1. Data are presented as mean ± standard deviation (SD), median (interquartile range), or n (%)
  2. Abbreviations: FT3, free triiodothyronine; FT4, free thyroxine; DBP, diastolic blood pressure; SBP, systolic blood pressure; BMI, body mass index; FPG, fasting plasma glucose; HbA1c, glycated hemoglobin; LDL, low-density lipoprotein; HDL, high-density lipoprotein; TSH, thyrotropin; VFA, visceral fat area; SFA, subcutaneous fat area; GLP-1 RA, glucagon-like peptide-1 receptor agonist
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Lipids in Health and Disease

ISSN: 1476-511X