Fig. 2
From: Identification of oxylipins and lipid mediators in pulmonary embolism
Cloud and rain plots illustrating the differences in serum lipid levels between the PE group (n = 555) and the HC group (n = 200), along with a heatmap showing the correlation analysis between serum lipid levels and coagulation-related laboratory indicators within the PE group. (A) Cloud and rain plot showing the difference in serum TC levels between the PE group and HC group. (B) Cloud and rain plot showing the difference in serum HDL-C levels between the PE group and HC group. (C) Cloud and rain plot showing the difference in serum LDL-C levels between the PE group and HC group. (D) Cloud and rain plot showing the difference in serum apoA levels between the PE group and HC group. (E) Cloud and rain plot showing the difference in serum apoB levels between the PE group and HC group. (F) Cloud and rain plot showing the difference in serum triglyceride (TG) levels between the PE group and HC group (Mann-Whitney U test for quantitative data comparison between two groups, **** represents P < 0.0001, ns represents no significance). (G) Heatmap showing the correlation between serum lipid levels (6 items) and coagulation-related indicators (5 items). The legend represents the correlation coefficient, with red and blue indicating positive and negative correlations, respectively, and the depth of color indicating the degree of correlation. The presence of “*” indicates an absolute correlation coefficient (|r| > 0.3, ****P < 0.0001, Spearman rank correlation analysis). (H) Heatmap showing the correlation between serum lipid levels (6 items) and coagulation factor levels. The legend represents the correlation coefficient, with red and blue indicating positive and negative correlations, respectively, and the depth of color indicating the degree of correlation. The presence of “*” indicates an absolute correlation coefficient (|r| > 0.3, ****P < 0.0001, Spearman rank correlation analysis)
Abbreviations: HC: healthy control; PE: pulmonary embolism; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; apoA: apolipoprotein A1; apoB: apolipoprotein B; TG: triglyceride; PT: prothrombin time; APTT: activated partial thromboplastin time; TT: thrombin time; FIB: fibrinogen; AT III: antithrombin III; PC: protein C; PS: protein S; vWF: von Willebrand factor; F VIII: factor VIII; F XII: factor XII