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Table 4 The subgroup analysis of the relationship between NHHR and risk of MACCEs

From: Association between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and cardiovascular outcomes in patients undergoing percutaneous coronary intervention: a retrospective study

Subgroups

quintiles of NHHR

P for interaction

Q1

Q2

Q3

Q4

Q5

< 2.15

2.15–2.77

2.78–3.39

3.40–4.22

> 4.22

Sex

0.830

Female

1(Ref)

0.78 (0.35,1.76)

0.79 (0.35,1.77)

1.41 (0.65,3.05)

1.43 (0.66,3.1)

 

Male

1(Ref)

0.79 (0.49,1.29)

0.57 (0.34,0.97)

0.9 (0.56,1.44)

1.05 (0.66,1.68)

 

Age, years

0.294

<65

1(Ref)

1.02 (0.56,1.80)

1.01 (0.55,1.85)

1.45 (0.83,2.53)

1.47 (0.85,2.55)

 

≥ 65

1(Ref)

0.64 (0.35,1.17)

0.40 (0.20,0.78)

0.67 (0.36,1.26)

0.92 (0.49,1.73)

 

Clinical presentation

0.690

STEMI

1(Ref)

1.42 (0.61,3.27)

0.56 (0.22,1.41)

1.03 (0.44,2.41)

1.25 (0.53,2.93)

 

SA

1(Ref)

0.53 (0.18,1.56)

0.49 (0.15,1.58)

0.96 (0.34,2.66)

1.05 (0.36,3.06)

 

NSTE-ACS

1(Ref)

0.67 (0.38,1.18)

0.71 (0.41,1.25)

1.02 (0.61,1.72)

1.16 (0.69,1.94)

 

Smoking status

0.934

No

1(Ref)

0.8 (0.48,1.32)

0.63 (0.37,1.07)

1.08 (0.66,1.75)

1.23 (0.76,1.99)

 

Yes

1(Ref)

0.83 (0.40,1.74)

0.63 (0.29,1.37)

0.85 (0.42,1.74)

0.99 (0.49,2.00)

 

Hypertension

0.635

No

1(Ref)

0.84 (0.46,1.51)

0.55 (0.29,1.05)

1.21 (0.69,2.13)

1.07 (0.59,1.93)

 

Yes

1(Ref)

0.77 (0.43,1.39)

0.72 (0.39,1.31)

0.87 (0.49,1.55)

1.21 (0.70,2.09)

 

Diabetes

0.858

No

1(Ref)

0.72 (0.45,1.15)

0.62 (0.38,1.02)

0.98 (0.63,1.54)

1.14 (0.73,1.79)

 

Yes

1(Ref)

1.33 (0.52,3.36)

0.82 (0.31,2.13)

1.02 (0.41,2.53)

1.35 (0.56,3.25)

 

Heart failure

0.576

No

1(Ref)

0.71 (0.45,1.13)

0.59 (0.37,0.95)

1.02 (0.67,1.56)

1.08 (0.71,1.65)

 

Yes

1(Ref)

1.34 (0.47,3.81)

1.01 (0.34,3.04)

0.86 (0.26,2.83)

1.56 (0.51,4.77)

 

CTO

0.133

No

1(Ref)

0.91 (0.58,1.43)

0.79 (0.50,1.26)

1.17 (0.76,1.82)

1.33 (0.86,2.06)

 

Yes

1(Ref)

0.40 (0.13,1.27)

0.11 (0.03,0.46)

0.44 (0.14,1.34)

0.54 (0.16,1.43)

 
  1. Note: The model was adjusted, if not stratified, for age, sex, smoking status, medical history of diseases (myocardial infarction, heart failure, atrial fibrillation, stroke, hypertension, diabetes), aspirin use, statin use, β-blocker use, 3-vessel disease, total stent length, and diameter of stents