Table 3 Top 20 CpGs that most significantly associated with LFC in the longitudinal meta-analysis in model 1

cg11024682

17

17,730,094

SREBF1

Body

S_Shelf

7.064

1.613E-12

++

cg00163198

11

130,767,760

SNX19

Body

OpenSea

6.32

2.608E-10

++

cg06500161

21

43,656,587

ABCG1

Body

S_Shore

6.2

5.642E-10

++

cg16740586

21

43,655,919

ABCG1

Body

S_Shore

5.804

6.465E-09

++

cg15659943

9

107,631,656

ABCA1

Body

OpenSea

5.352

8.702E-08

++

cg03694857

2

152,568,384

NEB

Body

OpenSea

5.149

2.614E-07

++

cg13449394

12

109,230,732

MIR619;SSH1

Body

OpenSea

5.058

4.248E-07

++

cg10819350

19

10,655,686

ATG4D

Body

S_Shore

5.047

4.496E-07

++

cg07162647

19

40,466,275

OpenSea

-5.026

5.014E-07

--

cg27243560

12

25,522,335

OpenSea

4.95

7.413E-07

++

cg21137557

5

115,314,451

LVRN

Body

OpenSea

-4.902

9.479E-07

--

cg00857282

6

16,130,727

MYLIP

Body

S_Shore

4.867

1.135E-06

++

cg27243685

21

43,642,366

ABCG1

Body; 5’UTR

S_Shelf

4.862

1.16E-06

++

cg00574958

11

68,607,622

CPT1A

5’UTR

N_Shore

-4.792

1.655E-06

--

cg12748148

2

30,549,065

OpenSea

-4.791

1.658E-06

--

cg13280734

11

57,252,275

SLC43A1

3’UTR

S_Shore

4.779

1.763E-06

++

cg12188928

17

27,309,139

SEZ6

Body

N_Shelf

4.767

1.87E-06

++

cg10558063

1

44,540,412

OpenSea

4.763

1.906E-06

++

cg07504977

10

102,131,012

N_Shelf

4.743

2.107E-06

++

cg07502358

13

78,168,218

SCEL

Body

OpenSea

-4.725

2.297E-06

--