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Table 1 Basic characteristics of the study participants

From: Longitudinal association of peripheral blood DNA methylation with liver fat content: distinguishing between predictors and biomarkers

 

Discovery

Replication

 
 

Baseline

(n = 358)

Follow-up

(n = 405)

Baseline

(n = 97)

Follow-up

(n = 125)

P†

Female, %

208 (58.1)

234 (57.8)

46 (47.4)

59 (47.2)

0.078

Age, years

61.2 (7.29)

65.5 (7.34)

61.9 (8.37)

66.8 (8.60)

0.407

Smoke, %

    

0.398

 Never

292 (81.6)

328 (81.0)

76 (78.4)

93 (74.4)

 

 Past

9 (2.5)

11 (2.7)

5 (5.2)

11 (8.8)

 

 Current

57 (15.9)

65 (16.0)

16 (16.5)

21 (16.8)

 

BMI, kg/m2

23.8 (2.96)

24.6 (3.08)

24.0 (2.44)

24.6 (3.05)

0.541

LFC, %

5.72

[2.21, 12.50]

5.75

[2.25, 14.28]

4.73

[1.75, 11.59]

5.87

[2.33, 12.33]

0.193

Follow-up time, years

4.10 (0.63)

4.39 (0.72)

0.003

LFC change, %

1.00 [-2.84, 6.45]

2.79 [-2.31, 7.64]

0.257

  1. †P indicates the significance of differences between discovery and replication cohorts at baseline
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Lipids in Health and Disease

ISSN: 1476-511X