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Table 3 Association between sleep and nighttime behavior and dyslipidemia at baseline and 12 months follow-up

From: Sleep and nighttime behavior disorders in older adults: associations with hypercholesterolemia and hypertriglyceridemia at baseline, and a predictive analysis of incident cases at 12 months follow-up

Characteristic

Model 1

Model 2

Model 3

 

N

Event

ORa (95% CIa)

P-value

N

Event

ORa (95% CIa)

P-value

N

Event

ORa (95% CIa)

P-value

Sleep disorders at baseline

 Cholesterol

2,216

357

 

0.744

2,031

335

 

0.412

2,031

335

 

0.571

  Normal (< 200 mg/dL)

  

—

   

—

   

—

 

  High (≥ 200 mg/dL)

  

1.04 (0.83, 1.31)

   

0.90 (0.70, 1.16)

   

0.93 (0.72, 1.20)

 

 Triglyceride

2,216

357

 

0.003

2,031

335

 

0.016

2,031

335

 

0.048

  Normal (< 150 mg/dL)

  

—

   

—

   

—

 

  High (≥ 150 mg/dL)

  

1.43 (1.13, 1.80)

   

1.36 (1.06, 1.74)

   

1.29 (1.00, 1.66)

 

 BMI (continuous value)

2,216

357

1.03 (1.00, 1.05)

0.030

2,031

335

1.03 (1.01, 1.06)

0.008

  

—

 

BMI categories

2,216

357

 

0.095

2,031

335

 

0.029

  

—

 

   Healthy Weight

  

—

   

—

   

—

 

   Underweight

  

1.12 (0.26, 3.43)

0.857

  

0.95 (0.21, 2.99)

0.934

  

—

 

   Overweight

  

1.12 (0.86, 1.47)

0.391

  

1.14 (0.86, 1.51)

0.371

  

—

 

   Obesity

  

1.47 (1.09, 1.99)

0.012

  

1.65 (1.18, 2.29)

0.003

  

—

 

Incident sleep disorders at 12 months follow-up

 Cholesterol

1,550

187

 

0.719

1,468

178

 

0.641

1,468

178

 

0.706

  Normal (< 200 mg/dL)

  

—

   

—

   

—

 

  High (≥ 200 mg/dL)

  

1.06 (0.77, 1.44)

   

1.08 (0.77, 1.52)

   

1.07 (0.76, 1.50)

 

 Triglyceride

1,550

187

 

0.066

1,468

178

 

0.167

1,468

178

 

0.122

  Normal (< 150 mg/dL)

  

—

   

—

   

—

 

  High (≥ 150 mg/dL)

  

1.35 (0.98, 1.85)

   

1.27 (0.90, 1.76)

   

1.31 (0.93, 1.83)

 

 BMI (continuous value)

1,550

187

0.98 (0.95, 1.01)

0.202

1,468

178

0.98 (0.95, 1.02)

0.417

  

—

 

BMI categories

1,550

187

 

0.046

1,468

178

 

0.090

  

—

 

   Healthy Weight

  

—

   

—

   

—

 

   Underweight

  

4.81 (1.23, 16.4)

0.014

  

4.15 (1.04, 14.6)

0.030

  

—

 

   Overweight

  

1.34 (0.95, 1.90)

0.101

  

1.35 (0.93, 1.95)

0.114

  

—

 

   Obesity

  

0.97 (0.61, 1.51)

0.891

  

1.02 (0.62, 1.66)

0.941

  

—

 
  1. Model 1: crude logistic regression analysis
  2. Model 2: adjusted for age, sex, racial profile, educational level, cognition-related main diagnosis, geriatric depression scale total score, APOE ε4 status
  3. Model 3: model 2 + BMI
  4. aOR Odds Ratio, CI Confidence Interval, BMI Body Mass Index
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Lipids in Health and Disease

ISSN: 1476-511X