Characteristic | ** Hypercholesterolemia ** | ** Hypertriglyceridemia ** | ||||
---|---|---|---|---|---|---|
Normal (< 200 mg/dL) N = 1,2961 | High (≥ 200 mg/dL) N = 9201 | P-value2 | Normal (< 150 mg/dL) N = 1,4911 | High (≥ 150 mg/dL) N = 7251 | P-value2 | |
Age (years) | 74 (69, 79) | 72 (67, 78) |  < 0.001 | 73 (68, 78) | 73 (67, 78) | 0.3 |
Sex |  |  |  < 0.001 |  |  | 0.4 |
 Female | 453 (35%) | 592 (64%) |  | 713 (48%) | 332 (46%) |  |
 Male | 843 (65%) | 328 (36%) |  | 778 (52%) | 393 (54%) |  |
Main cognitive diagnosis | Â | Â | 0.6 | Â | Â | 0.3 |
 Healthy controls | 465 (36%) | 321 (35%) |  | 543 (36%) | 243 (34%) |  |
 MCI | 623 (48%) | 437 (48%) |  | 698 (47%) | 362 (50%) |  |
 Dementia | 208 (16%) | 162 (18%) |  | 250 (17%) | 120 (17%) |  |
Educational level (years) | 16.00 (14.00, 18.00) | 16.00 (14.00, 18.00) | 0.4 | 16.00 (14.00, 18.00) | 16.00 (14.00, 18.00) |  < 0.001 |
Marital status | Â | Â | 0.004 | Â | Â | 0.6 |
 Currently married | 1,007 (78%) | 666 (72%) |  | 1,131 (76%) | 542 (75%) |  |
 Currently not married or unknown | 289 (22%) | 254 (28%) |  | 360 (24%) | 183 (25%) |  |
Home | Â | Â | 0.4 | Â | Â | 0.5 |
 House or appartment | 1,230 (95%) | 871 (95%) |  | 1,419 (95%) | 682 (94%) |  |
 Retirement or nursing institution | 47 (3.6%) | 29 (3.2%) |  | 47 (3.2%) | 29 (4.0%) |  |
 Other | 19 (1.5%) | 20 (2.2%) |  | 25 (1.7%) | 14 (1.9%) |  |
Racial profile |  |  | 0.6 |  |  |  < 0.001 |
 White | 1,140 (88%) | 812 (88%) |  | 1,294 (87%) | 658 (91%) |  |
 Black | 95 (7.3%) | 72 (7.8%) |  | 137 (9.2%) | 30 (4.1%) |  |
 Other | 61 (4.7%) | 36 (3.9%) |  | 60 (4.0%) | 37 (5.1%) |  |
APOE ε4 status |  |  | 0.024 |  |  | 0.3 |
 0 allele | 663 (56%) | 432 (51%) |  | 727 (53%) | 368 (55%) |  |
 1 allele | 411 (35%) | 324 (38%) |  | 489 (36%) | 246 (37%) |  |
 2 alleles | 104 (8.8%) | 97 (11%) |  | 145 (11%) | 56 (8.4%) |  |
 Missing values | 118 | 67 |  | 130 | 55 |  |
ADAS13 total score | 14 (9, 21) | 14 (8, 22) | 0.059 | 14 (9, 21) | 14 (9, 22) | 0.4 |
MMSE total score | 28.00 (26.00, 29.00) | 28.00 (26.00, 30.00) |  > 0.9 | 28.00 (26.00, 29.00) | 28.00 (26.00, 29.00) | 0.2 |
CDR-SB | 1.00 (0.00, 2.00) | 1.00 (0.00, 2.50) | 0.4 | 1.00 (0.00, 2.00) | 1.00 (0.00, 2.50) | 0.081 |
FAQ total score | 1.0 (0.0, 5.0) | 1.0 (0.0, 5.0) | 0.7 | 0.0 (0.0, 5.0) | 1.0 (0.0, 6.0) | 0.028 |
 Missing values | 1 | 4 |  | 4 | 1 |  |
GDS total score | 1.00 (0.00, 2.00) | 1.00 (0.00, 2.00) | 0.7 | 1.00 (0.00, 2.00) | 1.00 (0.00, 2.00) |  < 0.001 |
BMI | 26.7 (24.4, 29.8) | 25.5 (23.1, 28.7) |  < 0.001 | 25.7 (23.4, 28.6) | 27.5 (25.1, 30.9) |  < 0.001 |
Cholesterol (mg/dL) | 170 (151, 184) | 225 (212, 246) |  < 0.001 | 187 (162, 216) | 197 (172, 227) |  < 0.001 |
Triglyceride (mg/dL) | 115 (84, 162) | 127 (92, 183) |  < 0.001 | 98 (76, 120) | 203 (172, 255) |  < 0.001 |
Sleep disorders at baseline | 206 (16%) | 151 (16%) | 0.7 | 216 (14%) | 141 (19%) | 0.003 |
Sleep disorders at 12Â months | 188 (17%) | 139 (18%) | 0.7 | 199 (16%) | 128 (21%) | 0.025 |
 Missing values | 215 | 156 |  | 270 | 101 |  |