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Table 2 Comparison between study participants with and without dyslipidemia

From: Sleep and nighttime behavior disorders in older adults: associations with hypercholesterolemia and hypertriglyceridemia at baseline, and a predictive analysis of incident cases at 12 months follow-up

Characteristic

** Hypercholesterolemia **

** Hypertriglyceridemia **

Normal

(< 200 mg/dL)

N = 1,2961

High

(≥ 200 mg/dL)

N = 9201

P-value2

Normal

(< 150 mg/dL)

N = 1,4911

High

(≥ 150 mg/dL)

N = 7251

P-value2

Age (years)

74 (69, 79)

72 (67, 78)

 < 0.001

73 (68, 78)

73 (67, 78)

0.3

Sex

  

 < 0.001

  

0.4

 Female

453 (35%)

592 (64%)

 

713 (48%)

332 (46%)

 

 Male

843 (65%)

328 (36%)

 

778 (52%)

393 (54%)

 

Main cognitive diagnosis

  

0.6

  

0.3

 Healthy controls

465 (36%)

321 (35%)

 

543 (36%)

243 (34%)

 

 MCI

623 (48%)

437 (48%)

 

698 (47%)

362 (50%)

 

 Dementia

208 (16%)

162 (18%)

 

250 (17%)

120 (17%)

 

Educational level (years)

16.00 (14.00, 18.00)

16.00 (14.00, 18.00)

0.4

16.00 (14.00, 18.00)

16.00 (14.00, 18.00)

 < 0.001

Marital status

  

0.004

  

0.6

 Currently married

1,007 (78%)

666 (72%)

 

1,131 (76%)

542 (75%)

 

 Currently not married or unknown

289 (22%)

254 (28%)

 

360 (24%)

183 (25%)

 

Home

  

0.4

  

0.5

 House or appartment

1,230 (95%)

871 (95%)

 

1,419 (95%)

682 (94%)

 

 Retirement or nursing institution

47 (3.6%)

29 (3.2%)

 

47 (3.2%)

29 (4.0%)

 

 Other

19 (1.5%)

20 (2.2%)

 

25 (1.7%)

14 (1.9%)

 

Racial profile

  

0.6

  

 < 0.001

 White

1,140 (88%)

812 (88%)

 

1,294 (87%)

658 (91%)

 

 Black

95 (7.3%)

72 (7.8%)

 

137 (9.2%)

30 (4.1%)

 

 Other

61 (4.7%)

36 (3.9%)

 

60 (4.0%)

37 (5.1%)

 

APOE ε4 status

  

0.024

  

0.3

 0 allele

663 (56%)

432 (51%)

 

727 (53%)

368 (55%)

 

 1 allele

411 (35%)

324 (38%)

 

489 (36%)

246 (37%)

 

 2 alleles

104 (8.8%)

97 (11%)

 

145 (11%)

56 (8.4%)

 

 Missing values

118

67

 

130

55

 

ADAS13 total score

14 (9, 21)

14 (8, 22)

0.059

14 (9, 21)

14 (9, 22)

0.4

MMSE total score

28.00 (26.00, 29.00)

28.00 (26.00, 30.00)

 > 0.9

28.00 (26.00, 29.00)

28.00 (26.00, 29.00)

0.2

CDR-SB

1.00 (0.00, 2.00)

1.00 (0.00, 2.50)

0.4

1.00 (0.00, 2.00)

1.00 (0.00, 2.50)

0.081

FAQ total score

1.0 (0.0, 5.0)

1.0 (0.0, 5.0)

0.7

0.0 (0.0, 5.0)

1.0 (0.0, 6.0)

0.028

 Missing values

1

4

 

4

1

 

GDS total score

1.00 (0.00, 2.00)

1.00 (0.00, 2.00)

0.7

1.00 (0.00, 2.00)

1.00 (0.00, 2.00)

 < 0.001

BMI

26.7 (24.4, 29.8)

25.5 (23.1, 28.7)

 < 0.001

25.7 (23.4, 28.6)

27.5 (25.1, 30.9)

 < 0.001

Cholesterol (mg/dL)

170 (151, 184)

225 (212, 246)

 < 0.001

187 (162, 216)

197 (172, 227)

 < 0.001

Triglyceride (mg/dL)

115 (84, 162)

127 (92, 183)

 < 0.001

98 (76, 120)

203 (172, 255)

 < 0.001

Sleep disorders at baseline

206 (16%)

151 (16%)

0.7

216 (14%)

141 (19%)

0.003

Sleep disorders at 12 months

188 (17%)

139 (18%)

0.7

199 (16%)

128 (21%)

0.025

 Missing values

215

156

 

270

101

 
  1. ADAS13 Alzheimer’s Disease Assessment Score – 13 items, APOE ε4 Apolipoprotein E ε4, BMI Body-Mass Index (Weight in Kg / (Height in m)2), CDR- SB Clinical Dementia Rating Scale—sum of boxes, FAQ Functional Activities Questionnaire, GDS Geriatric Depression Scale, MCI Mild Cognitive Impairment, MMSE Mini-Mental Status Examination
  2. 1Median (IQR); n (%)
  3. 2Wilcoxon rank sum test; Pearson’s Chi-squared test