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Table 2 Terminal tissue weights and plasma hormones and NEFA levels in experiment 4. NEFA levels were determined in 5h-fasted mice on the days shown. Other measurements were in fed mice on day 77.

From: Prolonged treatment of genetically obese mice with conjugated linoleic acid improves glucose tolerance and lowers plasma insulin concentration: possible involvement of PPAR activation

 

Sunflower oil

1% Clarinol A80

2.5% Clarinol A80

Body length (mm)

95.0 ± 1.0

85.7 ± 0.3+

86.4 ± 1.4+

White adipose wt (g)

2.11 ± 0.15

0.63 ± 0.07+

0.19 ± 0.02+

Brown adipose wt (g)

0.74 ± 0.07

0.33 ± 0.04+

0.007 ± 0.005+

Liver wt (g)

4.96 ± 0.17

6.27 ± 0.58

6.77 ± 0.36*

Pancreas wt (g)

0.18 ± 0.01

0.20 ± 0.01

0.16 ± 0.02

NEFA (mM)

   

Day 14

3.20 ± 0.17

3.58 ± 0.07

3.27 ± 0.13

Day 35

3.46 ± 0.42

3.93 ± 0.22

2.82 ± 0.40

Day 70

2.90 ± 0.19

3.44 ± 0.13*

1.92 ± 0.09+

Plasma adiponectin (ng/ml)

35.6 ± 7.0

8.2 ± 1.2+

0.89 ± 0.13+

Plasma TNFα (pg/ml)

34.0 ± 5.7

33.0 ± 2.4

42.3 ± 7.1

  1. * P < 0.05; + P < 0.001; n = 6
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Lipids in Health and Disease

ISSN: 1476-511X