Hypercholesterolemia and apolipoprotein B expression: Regulation by selenium status

Table 2 Total cholesterol (mg/dl), LDL-cholesterol (mg/dl) and apolipoprotein B (A₄₀₅) levels in serum after 1 and 2 months of control and high cholesterol diet (HCD) feeding schedule.

Treatment period	Se deficient group		Se adequate group		Se excess group
	Control Ia	HCD Ib	Control IIa	HCD IIb	Control IIIa	HCD IIIb
Cholesterol
1 month	107.87 ± 6.87^DDD	246.54 ± 11.96^##***	83.62 ± 5.45	215.23 ± 13.45***	74.43 ± 6.28^L	184.29 ± 11.73^***BB
2 months	120.23 ± 9.53^DDDA	295.14 ± 13.43^##***AAA	85.23 ± 5.24	269.82 ± 10.67^***AAA	62.73 ± 5.38^AALLL	165.34 ± 10.60^***BBBA
LDL
1 month	41.47 ± 4.23^DDD	94.82 ± 7.38^#***	32.16 ± 2.29	82.78 ± 7.17***	28.62 ± 2.42^L	70.88 ± 5.36^***BB
2 months	48.35 ± 3.71^ADDD	113.50 ± 9.16^#***A	32.78 ± 2.75	99.73 ± 9.32^***A	24.12 ± 2.06^AALLL	60.59 ± 5.83^***BBBAA
ApoB
1 month	0.195 ± 0.018	0.198 ± 0.019	0.191 ± 0.017	0.196 ± 0.016	0.189 ± 0.016	0.193 ± 0.018
2 months	0.287 ± 0.024^DDDAAA	0.345 ± 0.028^**AAA##	0.196 ± 0.016	0.275 ± 0.023^***AAA	0.130 ± 0.011^AAALLL	0.162 ± 0.015^**AABBB

Data is represented as mean ± SD from 6 observations.
**p<0.01, ***p<0.001 represent comparison between control and HCD groups; ^Ap<0.05, ^AAp<0.01, ^AAAp<0.001 comparison between 1 and 2 months; ^DDp<0.01, ^DDDp<0.001 comparison between group Ia and IIa; ^##p<0.01, ^###p<0.001 comparison between group Ib and IIb; ^Lp<0.05, ^LLp<0.01, ^LLLp<0.001 comparison between group IIa and IIIa; ^BBp<0.01, ^BBBp<0.001 comparison between group IIb and IIIb.

ISSN: 1476-511X